Riedler Karoline, Hecker Andrzej, Bauer Birgit, Tax Christa, Gmainer Daniel Georg, Pignet Anna-Lisa, Kamolz Lars-Peter, Lumenta David Benjamin
University Hospital Graz, 8036 Graz, Austria.
Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, 8036 Graz, Austria.
Clin Pract. 2023 May 25;13(3):648-655. doi: 10.3390/clinpract13030059.
Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar quality in healed split-thickness skin graft donor sites.
A single-center blinded randomized controlled study was performed on 30 patients with healed split-thickness skin graft donor site. The patients were randomly allocated into blended regeneration oil ( = 14) and pure almond oil ( = 16) groups. Application of the assigned oil occurred twice a day for 6 months. Scarring (Patient and Observer Scar Assessment Scale), itching (ITCH Assessment Scale) and scar discoloration (colorimetry) of the donor sites were assessed after 1, 3 and 6 months.
We found no statistically significant differences between the groups in any applied parameter. We observed comparable outcomes (scar quality, itchiness, colorit) in healed split-thickness skin graft donor sites for both oils.
Regeneration oil and control oil presented comparable results regarding scar quality, itchiness and colorit in healed split-thickness skin graft donor sites after 6 months of application. Both oils are suitable for skin/scar care in split-thickness skin graft donor sites.
精油是一种辅助治疗方法，在瘢痕护理中可发挥重要作用。本研究旨在评估并比较一种新的精油（再生油）与对照组对愈合的中厚皮片供皮区瘢痕质量的疗效。
对30例中厚皮片供皮区已愈合的患者进行了一项单中心双盲随机对照研究。患者被随机分为混合再生油组（n = 14）和纯杏仁油组（n = 16）。每天涂抹指定的油2次，持续6个月。在1、3和6个月后评估供皮区的瘢痕形成情况（患者和观察者瘢痕评估量表）、瘙痒情况（瘙痒评估量表）和瘢痕变色情况（比色法）。
我们发现在任何应用参数上两组之间均无统计学显著差异。我们观察到两种油在愈合的中厚皮片供皮区的结果（瘢痕质量、瘙痒程度、颜色）具有可比性。
应用6个月后，再生油和对照油在愈合的中厚皮片供皮区的瘢痕质量、瘙痒程度和颜色方面呈现出可比的结果。两种油均适用于中厚皮片供皮区的皮肤/瘢痕护理。
