Włodarski K, Jakóbisiak M
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):1027-31.
Following heterotopic osteogenesis by implantation of xenogeneic epithelia (FL and WISH cell line, transitional epithelium of dog) in mice a biogenesis of hemopoietic tissue among induced ossicles is observed. Precursors and mature forms of all types of blood cells are found in the induced bone marrow. The concentration of lymphocytes in the induced bone marrow is higher, and that of erythropoietic cells lower as compared with orthotopic femur bone marrow. The yield of myeloid cells varied from 0.14 to 3.61 x 10(6) cells per induced bone-containing nodule.
通过在小鼠体内植入异种上皮(FL和WISH细胞系、狗的移行上皮)诱导异位骨形成后,在诱导形成的小骨中观察到造血组织的生物发生。在诱导的骨髓中发现了所有类型血细胞的前体和成熟形式。与原位股骨骨髓相比,诱导骨髓中淋巴细胞的浓度较高,而红细胞生成细胞的浓度较低。每个含有诱导骨的结节中髓样细胞的产量在0.14至3.61×10⁶个细胞之间。