Zhang Xinyuan, Zhao Jiulong, Xie Pei, Wang Shige
School of Health Science and Engineering, University of Shanghai for Science and Technology, No. 516 Jungong Road, Shanghai 200093, China.
Department of Gastroenterology, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Shanghai 200433, China.
J Funct Biomater. 2023 Jun 12;14(6):320. doi: 10.3390/jfb14060320.
Recently, electrical stimulation, as a non-pharmacological physical stimulus, has been widely exploited in biomedical and clinical applications due to its ability to significantly enhance cell proliferation and differentiation. As a kind of dielectric material with permanent polarization characteristics, electrets have demonstrated tremendous potential in this field owing to their merits of low cost, stable performance, and excellent biocompatibility. This review provides a comprehensive summary of the recent advances in electrets and their biomedical applications. We first provide a brief introduction to the development of electrets, as well as typical materials and fabrication methods. Subsequently, we systematically describe the recent advances of electrets in biomedical applications, including bone regeneration, wound healing, nerve regeneration, drug delivery, and wearable electronics. Finally, the present challenges and opportunities have also been discussed in this emerging field. This review is anticipated to provide state-of-the-art insights on the electrical stimulation-related applications of electrets.
近年来，电刺激作为一种非药物性物理刺激，因其能够显著促进细胞增殖和分化，已在生物医学和临床应用中得到广泛应用。作为一种具有永久极化特性的介电材料，驻极体因其成本低、性能稳定和生物相容性优异等优点，在该领域展现出巨大潜力。本文综述了驻极体及其生物医学应用的最新进展。我们首先简要介绍了驻极体的发展历程、典型材料和制备方法。随后，系统地描述了驻极体在生物医学应用中的最新进展，包括骨再生、伤口愈合、神经再生、药物递送和可穿戴电子设备。最后，还讨论了这一新兴领域当前面临的挑战和机遇。本文旨在为驻极体与电刺激相关的应用提供最新见解。
