Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations.
作者信息
Kunvarjee Binni, Bidgoli Alan, Madan Rebecca Pellett, Vidal Esther, McAvoy Devin, Hosszu Kinga K, Scaradavou Andromachi, Spitzer Barbara G, Curran Kevin J, Cancio Maria, Harris Andrew C, O'Reilly Richard J, Kung Andrew L, Prockop Susan, Boelens Jaap Jan, Oved Joseph H
机构信息
Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY.
Pediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
出版信息
J Allergy Clin Immunol. 2023 Sep;152(3):815-817. doi: 10.1016/j.jaci.2023.05.016. Epub 2023 Jun 26.
Abstract
摘要
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本文引用的文献
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Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure.骨髓衰竭患儿造血细胞移植中移植物排斥标志物。
Blood Adv. 2021 Nov 23;5(22):4594-4604. doi: 10.1182/bloodadvances.2021005231.
2
Gain-of-Function Mutations Cause High Total STAT1 Levels With Normal Dephosphorylation.功能获得性突变导致总 STAT1 水平升高，同时磷酸化正常。
Front Immunol. 2019 Jul 10;10:1433. doi: 10.3389/fimmu.2019.01433. eCollection 2019.
3
Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation.干扰素-γ 在异基因造血干细胞移植后免疫介导的移植物失败中的作用。
Haematologica. 2019 Nov;104(11):2314-2323. doi: 10.3324/haematol.2019.216101. Epub 2019 Feb 21.
4
Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations.信号转导子和转录激活子 1 基因突变功能获得型患者的造血干细胞移植。
J Allergy Clin Immunol. 2018 Feb;141(2):704-717.e5. doi: 10.1016/j.jaci.2017.03.049. Epub 2017 Jun 7.
5
Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype.杂合性信号转导和转录激活因子1（STAT1）功能获得性突变是一种临床表型出人意料广泛的疾病的基础。
Blood. 2016 Jun 23;127(25):3154-64. doi: 10.1182/blood-2015-11-679902. Epub 2016 Apr 25.
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