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Emapalumab for the Treatment of Immune-Mediated Graft Failure after HSCT.

作者信息

Merli Pietro, Jodele Sonata, Cook Eleanor, Myers Kasiani C, Lane Adam, Ryhänen Samppa, Cefalo Maria Pia, Quagliarella Francesco, Davies Stella M, Teusink-Cross Ashley, Aguayo-Hiraldo Paibel, Alexander Jessie L, Szabolcs Paul, Kohorst Mira, Corsetti Tiziana, Locatelli Franco, Sabulski Anthony

机构信息

Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

出版信息

Bone Marrow Transplant. 2025 Mar;60(3):406-411. doi: 10.1038/s41409-024-02487-w. Epub 2024 Dec 3.

DOI:10.1038/s41409-024-02487-w
PMID:39627345
Abstract
摘要

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本文引用的文献

1
Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations.依玛帕鲁单抗作为STAT1功能获得性突变患者造血细胞移植的桥梁治疗。
J Allergy Clin Immunol. 2023 Sep;152(3):815-817. doi: 10.1016/j.jaci.2023.05.016. Epub 2023 Jun 26.
2
Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure.骨髓衰竭患儿造血细胞移植中移植物排斥标志物。
Blood Adv. 2021 Nov 23;5(22):4594-4604. doi: 10.1182/bloodadvances.2021005231.
3
Identification of New Soluble Factors Correlated With the Development of Graft Failure After Haploidentical Hematopoietic Stem Cell Transplantation.
鉴定与单倍体造血干细胞移植后移植物失功发展相关的新可溶性因子。
Front Immunol. 2021 Jan 29;11:613644. doi: 10.3389/fimmu.2020.613644. eCollection 2020.
4
Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated bacillus Calmette-Guérin infection.依马芦单抗治疗抗腺苷脱氨酶缺乏症严重联合免疫缺陷病患者伴难治性噬血细胞性淋巴组织细胞增生症相关移植物衰竭和播散性卡介苗感染。
Haematologica. 2021 Feb 1;106(2):641-646. doi: 10.3324/haematol.2020.255620.
5
Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.埃马珠单抗治疗原发性噬血细胞性淋巴组织细胞增生症患儿。
N Engl J Med. 2020 May 7;382(19):1811-1822. doi: 10.1056/NEJMoa1911326.
6
Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation.干扰素-γ 在异基因造血干细胞移植后免疫介导的移植物失败中的作用。
Haematologica. 2019 Nov;104(11):2314-2323. doi: 10.3324/haematol.2019.216101. Epub 2019 Feb 21.
7
Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation.造血干细胞移植患者病毒感染的过继细胞治疗策略。
Cells. 2019 Jan 14;8(1):47. doi: 10.3390/cells8010047.
8
Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies.血液系统恶性肿瘤清髓性异基因造血细胞移植后的原发性移植物功能衰竭
Leukemia. 2015 Aug;29(8):1754-62. doi: 10.1038/leu.2015.75. Epub 2015 Mar 16.
9
IFN-gamma mediates the rejection of haematopoietic stem cells in IFN-gammaR1-deficient hosts.γ干扰素在γ干扰素受体1缺陷宿主中介导造血干细胞的排斥反应。
PLoS Med. 2008 Jan 29;5(1):e26. doi: 10.1371/journal.pmed.0050026.