Cafiero M, Scalzone A M, Borgia M, Costantino N F, Fiorenza B, Eramo A N
Minerva Med. 1986 Jul 14;77(28-29):1377-80.
The 24 hour study was carried out on 34 subjects, 17 cardiopathy 13 male and 4 female, mean age 56 +/- 14) and 17 normal (10 male and 7 female, mean age 41 +/- 18) with, on average, over 30 PVC/h in the dynamic ECG: no statistically significant difference in mean PVC/h was recorded between the two groups. Single cosinor analysis demonstrated a statistically significant circadian rhythm (p less than 0.05) in 11 cardiopathic (64.7%) and 13 normal subjects (76.4%). Population mean cosinor failed to demonstrate a significant rhythm in either of the two groups. Results suggest that personal circadian rhythms should be studied to identify the most appropriate antiarrhythmic treatment.
对34名受试者进行了为期24小时的研究，其中17名心脏病患者（13名男性和4名女性，平均年龄56±14岁）和17名正常人（10名男性和7名女性，平均年龄41±18岁），动态心电图平均每小时室性早搏超过30次：两组之间每小时室性早搏的平均值无统计学显著差异。单余弦分析显示，11名心脏病患者（64.7%）和13名正常人（76.4%）存在统计学显著的昼夜节律（p<0.05）。总体平均余弦分析未能在两组中的任何一组中显示出显著节律。结果表明，应研究个体昼夜节律以确定最合适的抗心律失常治疗方法。
