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电子套装在神经系统疾病中的应用与疗效:一项具有临床意义的系统评价

Use and Effectiveness of Electrosuit in Neurological Disorders: A Systematic Review with Clinical Implications.

作者信息

Perpetuini David, Russo Emanuele Francesco, Cardone Daniela, Palmieri Roberta, De Giacomo Andrea, Pellegrino Raffaello, Merla Arcangelo, Calabrò Rocco Salvatore, Filoni Serena

机构信息

Department of Engineering and Geology, University G. D'Annunzio of Chieti-Pescara, 65127 Pescara, Italy.

Padre Pio Foundation and Rehabilitation Centers, 71013 San Giovanni Rotondo, Italy.

出版信息

Bioengineering (Basel). 2023 Jun 2;10(6):680. doi: 10.3390/bioengineering10060680.

DOI:10.3390/bioengineering10060680
PMID:37370612
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10294955/
Abstract

Electrical stimulation through surface electrodes is a non-invasive therapeutic technique used to improve voluntary motor control and reduce pain and spasticity in patients with central nervous system injuries. The Exopulse Mollii Suit (EMS) is a non-invasive full-body suit with integrated electrodes designed for self-administered electrical stimulation to reduce spasticity and promote flexibility. The EMS has been evaluated in several clinical trials with positive findings, indicating its potential in rehabilitation. This review investigates the effectiveness of the EMS for rehabilitation and its acceptability by patients. The literature was collected through several databases following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. Positive effects of the garment on improving motor functions and reducing spasticity have been shown to be related to the duration of the administration period and to the dosage of the treatment, which, in turn, depend on the individual's condition and the treatment goals. Moreover, patients reported wellbeing during stimulation and a muscle-relaxing effect on the affected limb. Although additional research is required to determine the efficacy of this device, the reviewed literature highlights the EMS potential to improve the motor capabilities of neurological patients in clinical practice.

摘要

通过表面电极进行电刺激是一种非侵入性治疗技术,用于改善中枢神经系统损伤患者的自主运动控制,减轻疼痛和痉挛。Exopulse Mollii套装(EMS)是一种非侵入性全身套装,带有集成电极,设计用于自我实施电刺激,以减轻痉挛并促进灵活性。EMS已在多项临床试验中进行了评估,结果呈阳性,表明其在康复方面的潜力。本综述调查了EMS在康复方面的有效性及其受患者的接受程度。按照系统评价和Meta分析的首选报告项目(PRISMA)声明,通过多个数据库收集了相关文献。已证明该套装对改善运动功能和减轻痉挛的积极作用与给药期的持续时间和治疗剂量有关,而这又取决于个体状况和治疗目标。此外,患者报告在刺激过程中感觉良好,且患肢有肌肉放松的效果。尽管需要进一步研究来确定该设备的疗效,但综述文献强调了EMS在临床实践中改善神经疾病患者运动能力的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/476788b12a54/bioengineering-10-00680-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/5133c78de23b/bioengineering-10-00680-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/e83d3b21357e/bioengineering-10-00680-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/476788b12a54/bioengineering-10-00680-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/5133c78de23b/bioengineering-10-00680-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/e83d3b21357e/bioengineering-10-00680-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c420/10294955/476788b12a54/bioengineering-10-00680-g003.jpg

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Modulation of spinal circuits following phase-dependent electrical stimulation of afferent pathways.传入通路相位依赖性电刺激后脊髓回路的调制
J Neural Eng. 2023 Jan 27;20(1). doi: 10.1088/1741-2552/acb087.
3
Identification of Functional Cortical Plasticity in Children with Cerebral Palsy Associated to Robotic-Assisted Gait Training: An fNIRS Study.
EXOPULSE Mollii套装对多发性硬化症患者运动功能的影响——一项随机假对照交叉试验。
Mult Scler J Exp Transl Clin. 2025 Jun 19;11(2):20552173251348304. doi: 10.1177/20552173251348304. eCollection 2025 Apr-Jun.
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The effect of the EXOPULSE Mollii Suit on pain and fibromyalgia-related symptoms-A randomized sham-controlled crossover trial.EXOPULSE Mollii套装对疼痛及纤维肌痛相关症状的影响——一项随机假对照交叉试验
Eur J Pain. 2025 Feb;29(2):e4729. doi: 10.1002/ejp.4729. Epub 2024 Sep 18.
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