Nordin U, Lyttkens L
Arch Otorhinolaryngol. 1979;222(2):119-25. doi: 10.1007/BF00469751.
A new parachute cuff has been tested in combination with a positive end-expiratory pressure (PEEP) on mongrel dogs. During positive-pressure ventilation the intracuff and intratracheal pressures showed synchronous, identical pressure variations, and therefore theoretically with this type of cuff the pressure against the tracheal wall would be minimal. The cuff provided a seal against gas leakage from the lungs throughout the entire test period, i.e., for up to 7 h. To avoid aspiration of mouth contents during the passive exhalation phase, different amounts of PEEP were tested. A PEEP of 4.0--8.0 cm H2O always produced a seal against a column of fluid in the mouth exerting a hydrostatic pressure of 5.4--8.8 cm H2O against the cuff. This seal was maintained during the whole test period. No difference in sealing capacity was found when the cuff was used with a normal respiratory frequency (20/min) and with high-frequency positive-pressure ventilation (60/min). When the PEEP is eliminated, e.g., when the respirator is disconnected for suction of the endotracheal tube, the sealing effect will be abolished. As the cuff extends up into the larynx there will be no pooling of fluid above the cuff. The risk of aspiration can therefore be diminished by suction of oral cavity before disconnecting the respirator. With the use of the pneumatic valve principle together with high-frequency positive-pressure ventilation, an open respirator system can produce a continuous PEEP, thereby preventing aspiration even during suctioning of the tracheal tube.
一种新型降落伞式气管套囊已与呼气末正压(PEEP)相结合,在杂种犬身上进行了测试。在正压通气期间,套囊内和气管内压力显示出同步、相同的压力变化,因此从理论上讲,使用这种类型的套囊时,对气管壁的压力将降至最低。在整个测试期间,即长达7小时内,该套囊均能有效防止气体从肺部泄漏。为避免在被动呼气阶段口腔内容物误吸,对不同水平的PEEP进行了测试。4.0 - 8.0 cm H₂O的PEEP总能有效防止口腔内水柱对套囊产生5.4 - 8.8 cm H₂O的静水压力。在整个测试期间,这种密封效果一直保持。当套囊用于正常呼吸频率(20次/分钟)和高频正压通气(60次/分钟)时,密封能力没有差异。当消除PEEP时,例如在断开呼吸机以抽吸气管导管时,密封效果将消失。由于套囊向上延伸至喉部,套囊上方不会积液。因此,在断开呼吸机之前抽吸口腔可以降低误吸风险。通过使用气动阀原理并结合高频正压通气,开放式呼吸机能产生持续的PEEP,从而即使在抽吸气管导管时也能防止误吸。