Weitl J, Bettstetter H
Ldt. Pfleger für innerbetriebliche Fort- und Weiterbildung, Kreiskrankenhaus Alt/Neuötting.
Anaesthesist. 1994 Jun;43(6):359-63. doi: 10.1007/s001010050068.
A new closed tracheo-bronchial suction system was evaluated. With this device the patient need not be disconnected from the ventilator during suctioning, and can thus have a continuous supply of oxygen. The closed suction system is attached to the patient's endotracheal tube and ventilator Y-piece. The catheter, which is enveloped by a plastic sheet, can remain connected to the patient for as long as 24 h (Fig. 1). MATERIALS AND METHODS. In the medical and surgical intensive care unit of Alt/Neuötting General District Hospital, 39 trials on 16 mechanically ventilated patients receiving more than 8 cm H2O positive end-expiratory pressure (PEEP) and/or more than 60% FiO2 were performed. Each subject was suctioned using the open and closed methods. Arterial blood gases were obtained through an indwelling catheter before suctioning and then 1, 5, and 15 min after suctioning. Open suctioning: After 2 min preoxygenation with 100% oxygen the patient was disconnected from the ventilator, the suction catheter was inserted and the subject suctioned for a maximum of 15 s, then manually ventilated four times and reconnected. Closed suctioning: After preoxygenation the patient was suctioned without disconnection by means of the closed suction system. Statistical analysis was done by the two-tailed t-test on individual paired differences or by Student's t-test. P values of less than 0.05 were accepted as significant.
Patients were subdivided according to the PEEP level used (less or more than 8 cm H2O) and analysed separately. One minute after suctioning (T1) arterial pO2 was found to increase significantly for the open-system method when PEEP ventilation was < or = 8 cm H2O (Table 1) and for the closed system method when PEEP ventilation was both < or = 8 cm H2O (Table 1) and > 8 cm H2O (Table 2). Five (T5) and 15 (T15) min after suctioning, pO2 dropped significantly compared to baseline values in the open-system method when PEEP was > 8 cm H2O (Table 2). PO2 values 15 min after closed suctioning with PEEP > 8 cm H2O were significantly higher than those after open suctioning (Table 2). After the pO2 differences were formed between baseline and values 1, 5, and 15 min after suctioning, significant differences between open- and closed-system suctioning were found for PEEP > 8 cm H2O at T1, T5, and T15 (Table 2, Fig. 3). DISCUSSION. The increase in pO2 as a positive effect of preoxygenation with 100% oxygen before suctioning was less marked for open-system suctioning with PEEP > 8 cm H2O because FiO2, measured at the ventilator Y-piece, was abruptly reduced after disconnection and simultaneously PEEP was lost. As a consequence, pO2 values fell significantly 5 and 15 min after suctioning in this situation, whereas for all the other conditions pO2 reached baseline as well as slightly higher values. Patients with severe respiratory insufficiency need continuous positive airway pressure to keep unstable alveoli patent. Every maneuver that reduces intra-alveolar pressure may precipitate alveolar collapse. However, in the diseased lung closed alveoli may not re-expand at once when pressure is re-established. Therefore, closed-system suctioning may help to prevent prolonged deterioration of oxygenation in patients with severe respiratory failure.
对一种新型封闭式气管支气管吸引系统进行了评估。使用该装置,患者在吸引过程中无需与呼吸机断开连接,因此可持续获得氧气供应。封闭式吸引系统连接到患者的气管内导管和呼吸机Y形接头。被塑料薄膜包裹的导管可与患者保持连接长达24小时(图1)。材料与方法:在阿尔特/新厄廷综合区医院的内科和外科重症监护病房,对16例接受呼气末正压(PEEP)大于8 cmH₂O和/或吸入氧浓度(FiO₂)大于60%的机械通气患者进行了39次试验。对每个受试者分别采用开放式和封闭式方法进行吸引。在吸引前通过留置导管获取动脉血气,然后在吸引后1、5和15分钟再次获取。开放式吸引:用100%氧气预充氧2分钟后,将患者与呼吸机断开连接,插入吸引导管,对受试者进行最多15秒的吸引,然后手动通气4次并重新连接。封闭式吸引:预充氧后,通过封闭式吸引系统在不中断连接的情况下对患者进行吸引。采用双尾t检验对个体配对差异进行统计分析,或采用学生t检验。P值小于0.05被认为具有统计学意义。
根据所使用的PEEP水平(小于或大于8 cmH₂O)对患者进行分组并分别分析。当PEEP通气≤8 cmH₂O时,开放式吸引方法在吸引后1分钟(T1)时动脉血氧分压(pO₂)显著升高(表1);当PEEP通气≤8 cmH₂O(表1)和>8 cmH₂O(表2)时,封闭式吸引方法在吸引后1分钟时动脉pO₂也显著升高。当PEEP>8 cmH₂O时,开放式吸引方法在吸引后5分钟(T5)和15分钟(T15)时,pO₂与基线值相比显著下降(表2)。当PEEP>8 cmH₂O时,封闭式吸引后15分钟时的pO₂值显著高于开放式吸引后的pO₂值(表2)。在形成吸引前基线值与吸引后1、5和15分钟时的pO₂差值后,发现当PEEP>8 cmH₂O时,在T1、T5和T15时开放式和封闭式吸引之间存在显著差异(表2,图3)。讨论:对于PEEP>8 cmH₂O的开放式吸引,由于在断开连接后在呼吸机Y形接头处测得的FiO₂突然降低,同时PEEP消失,因此在吸引前用100%氧气预充氧的积极作用即pO₂的升高不太明显。因此,在这种情况下,吸引后5分钟和15分钟时pO₂值显著下降,而在所有其他情况下,pO₂达到基线值以及略高的值。患有严重呼吸功能不全的患者需要持续气道正压通气以保持不稳定肺泡开放。任何降低肺泡内压的操作都可能导致肺泡塌陷。然而,在患病肺中,当压力重新建立时,闭合的肺泡可能不会立即重新扩张。因此,封闭式吸引可能有助于防止严重呼吸衰竭患者的氧合长期恶化。