Rijks Jesse H J, Lankveld Theo, Manusama Randolph, Broers Bernard, Stipdonk Antonius M W van, Chaldoupi Sevasti Maria, Bekke Rachel M A Ter, Schotten Ulrich, Linz Dominik, Luermans Justin G L M, Vernooy Kevin
Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre (MUMC+), 6229 HX Maastricht, The Netherlands.
Department of Cardiology, Zuyderland Medical Centre, 6419 PC Heerlen, The Netherlands.
J Clin Med. 2023 Jun 13;12(12):4028. doi: 10.3390/jcm12124028.
Implantation of a permanent pacemaker and atrioventricular (AV) node ablation (pace-and-ablate) is an established approach for rate and symptom control in elderly patients with symptomatic atrial fibrillation (AF). Left bundle branch area pacing (LBBAP) is a physiological pacing strategy that might overcome right ventricular pacing-induced dyssynchrony. In this study, the feasibility and safety of performing LBBAP and AV node ablation in a single procedure in the elderly was investigated.
Consecutive patients with symptomatic AF referred for pace-and-ablate underwent the treatment in a single procedure. Data on procedure-related complications and lead stability were collected at regular follow-up at one day, ten days and six weeks after the procedure and continued every six months thereafter.
25 patients (mean age 79.2 ± 4.2 years) were included and underwent successful LBBAP. In 22 (88%) patients, AV node ablation and LBBAP were performed in the same procedure. AV node ablation was postponed in two patients due to lead-stability concerns and in one patient on their own request. No complications related to the single-procedure approach were observed with no lead-stability issues at follow-up.
LBBAP combined with AV node ablation in a single procedure is feasible and safe in elderly patients with symptomatic AF.
植入永久性起搏器并进行房室(AV)结消融(起搏并消融)是老年有症状心房颤动(AF)患者控制心率和症状的既定方法。左束支区域起搏(LBBAP)是一种生理性起搏策略,可能克服右心室起搏引起的不同步。在本研究中,探讨了在老年患者中单次进行LBBAP和AV结消融的可行性和安全性。
因起搏并消融而转诊的有症状AF连续患者接受单次治疗。在术后1天、10天和6周定期随访时收集与手术相关的并发症和导线稳定性数据,此后每6个月继续收集。
纳入25例患者(平均年龄79.2±4.2岁),均成功进行了LBBAP。22例(88%)患者在同一手术中进行了AV结消融和LBBAP。2例患者因导线稳定性问题推迟了AV结消融,1例患者自行要求推迟。随访期间未观察到与单次手术方法相关的并发症,也没有导线稳定性问题。
对于有症状的老年AF患者,单次进行LBBAP联合AV结消融是可行且安全的。