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单步手术方法行左束支区域起搏及房室结消融治疗老年症状性心房颤动患者

Left Bundle Branch Area Pacing and Atrioventricular Node Ablation in a Single-Procedure Approach for Elderly Patients with Symptomatic Atrial Fibrillation.

作者信息

Rijks Jesse H J, Lankveld Theo, Manusama Randolph, Broers Bernard, Stipdonk Antonius M W van, Chaldoupi Sevasti Maria, Bekke Rachel M A Ter, Schotten Ulrich, Linz Dominik, Luermans Justin G L M, Vernooy Kevin

机构信息

Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre (MUMC+), 6229 HX Maastricht, The Netherlands.

Department of Cardiology, Zuyderland Medical Centre, 6419 PC Heerlen, The Netherlands.

出版信息

J Clin Med. 2023 Jun 13;12(12):4028. doi: 10.3390/jcm12124028.

Abstract

BACKGROUND

Implantation of a permanent pacemaker and atrioventricular (AV) node ablation (pace-and-ablate) is an established approach for rate and symptom control in elderly patients with symptomatic atrial fibrillation (AF). Left bundle branch area pacing (LBBAP) is a physiological pacing strategy that might overcome right ventricular pacing-induced dyssynchrony. In this study, the feasibility and safety of performing LBBAP and AV node ablation in a single procedure in the elderly was investigated.

METHODS

Consecutive patients with symptomatic AF referred for pace-and-ablate underwent the treatment in a single procedure. Data on procedure-related complications and lead stability were collected at regular follow-up at one day, ten days and six weeks after the procedure and continued every six months thereafter.

RESULTS

25 patients (mean age 79.2 ± 4.2 years) were included and underwent successful LBBAP. In 22 (88%) patients, AV node ablation and LBBAP were performed in the same procedure. AV node ablation was postponed in two patients due to lead-stability concerns and in one patient on their own request. No complications related to the single-procedure approach were observed with no lead-stability issues at follow-up.

CONCLUSIONS

LBBAP combined with AV node ablation in a single procedure is feasible and safe in elderly patients with symptomatic AF.

摘要

背景

植入永久性起搏器并进行房室(AV)结消融(起搏并消融)是老年有症状心房颤动(AF)患者控制心率和症状的既定方法。左束支区域起搏(LBBAP)是一种生理性起搏策略,可能克服右心室起搏引起的不同步。在本研究中,探讨了在老年患者中单次进行LBBAP和AV结消融的可行性和安全性。

方法

因起搏并消融而转诊的有症状AF连续患者接受单次治疗。在术后1天、10天和6周定期随访时收集与手术相关的并发症和导线稳定性数据,此后每6个月继续收集。

结果

纳入25例患者(平均年龄79.2±4.2岁),均成功进行了LBBAP。22例(88%)患者在同一手术中进行了AV结消融和LBBAP。2例患者因导线稳定性问题推迟了AV结消融,1例患者自行要求推迟。随访期间未观察到与单次手术方法相关的并发症,也没有导线稳定性问题。

结论

对于有症状的老年AF患者,单次进行LBBAP联合AV结消融是可行且安全的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb3a/10299391/b7081d262227/jcm-12-04028-g001.jpg

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