Tran Marie, Ait Said Khelifa, Menahem Benjamin, Morello Rémy, Tillou Xavier
Urology Department, CHU de Caen, Avenue de la Côte de Nacre, 14000 Caen, France.
Abdominal Surgery Department, CHU de Caen, Avenue de la Côte de Nacre, 14000 Caen, France.
J Clin Med. 2023 Jun 14;12(12):4040. doi: 10.3390/jcm12124040.
Malabsorption is a consequence of gastric bypass (GB). GB increases the risk of kidney stone formation. This study aimed to evaluate the accuracy of a screening questionnaire for assessing the risk of lithiasis in this population. We performed a monocentric retrospective study to evaluate a screening questionnaire administered to patients who underwent gastric bypass surgery between 2014 and 2015. Patients were asked to answer a questionnaire that included 22 questions divided into four parts: medical history, episodes of renal colic before and after bypass surgery, and eating habits. A total of 143 patients were included in the study, and the mean age of the patients was 49.1 ± 10.8 years. The time between gastric bypass surgery and the completion of the questionnaire was 50.75 ± 4.95 months. The prevalence of kidney stones in the study population was 19.6%. We found that with a score of ≥6, the sensitivity and specificity were 92.9% and 76.5%, respectively. Positive and negative predictive values were 49.1% and 97.8%, respectively. The ROC curve showed an Area Under the Curve (AUC) of 0.932 ± 0.029 ( < 0.001). We developed a reliable and short questionnaire to identify patients at a high risk of kidney stones after gastric bypass. When the results of the questionnaire were equal to or greater than six, the patient was at a high risk of kidney stone formation. With a good predictive negative value, it could be used in daily practice to screen patients who have undergone gastric bypass and are at a high risk of renal lithiasis.
吸收不良是胃旁路手术（GB）的一个后果。胃旁路手术会增加肾结石形成的风险。本研究旨在评估一份筛查问卷在评估该人群结石形成风险方面的准确性。我们进行了一项单中心回顾性研究，以评估向2014年至2015年间接受胃旁路手术的患者发放的一份筛查问卷。患者被要求回答一份包含22个问题的问卷，这些问题分为四个部分：病史、旁路手术前后的肾绞痛发作情况以及饮食习惯。共有143名患者纳入研究，患者的平均年龄为49.1±10.8岁。胃旁路手术与问卷完成之间的时间为50.75±4.95个月。研究人群中肾结石的患病率为19.6%。我们发现，得分≥6时，敏感性和特异性分别为92.9%和76.5%。阳性预测值和阴性预测值分别为49.1%和97.8%。ROC曲线显示曲线下面积（AUC）为0.932±0.029（<0.001）。我们制定了一份可靠且简短的问卷，以识别胃旁路手术后有高肾结石风险的患者。当问卷结果等于或大于6时，患者有高肾结石形成风险。由于具有良好的阴性预测值，它可用于日常实践中筛查接受过胃旁路手术且有高肾石病风险的患者。
