Guys and St Thomas NHS Trust, London, UK.
Croydon University Hospital NHS Trust, London, UK.
Curr Urol Rep. 2021 May 24;22(6):34. doi: 10.1007/s11934-021-01046-w.
We aim to provide an up-to-date literature review to further characterise the association of kidney stone disease (KSD) with gastrointestinal (GI) surgery. As KSD is associated with significant morbidity, it is important to quantify and qualify this association to provide better care and management for the patient subgroup.
To perform a systematic review of the existing literature to evaluate the association of KSD following GI surgery.
A literature search was performed of the following databases: MEDLINE, EMBASE, Scopus, Google Scholar, Key Urology, Uptodate and Cochrane Trials from January 2000 to June 2020.
A total of 106 articles were identified, and after screening for titles, abstracts and full articles, 12 full papers were included. This involved a total of 9299 patients who underwent primary GI surgery. Over a mean follow-up period of 5.4 years (range: 1-14.4 years), 819 (8.8%) developed KSD, varying from 1.2 to 83% across studies. The mean time to stone formation was approximately 3 years (range: 0.5-9 years). In the 4 studies that reported on the management of KSD (n = 427), 38.6% went on to have urological intervention. There is a high incidence of KSD following primary GI surgery, and after a mean follow-up of 3 years, around 9% of patients developed KSD. While the GI surgery was done for obesity, inflammatory bowel disease or cancer, the risk of KSD should be kept in mind during follow-up, and prompt urology involvement with metabolic assessment, medical and or surgical management offered as applicable.
提供最新的文献综述，以进一步描述肾结石病（KSD）与胃肠（GI）手术的关系。由于 KSD 与显著的发病率有关，因此量化和确定这种关联对于为患者亚组提供更好的护理和管理非常重要。
对现有文献进行系统回顾，以评估 GI 手术后 KSD 的相关性。
对以下数据库进行文献检索：MEDLINE、EMBASE、Scopus、Google Scholar、Key Urology、Uptodate 和 Cochrane Trials，检索时间为 2000 年 1 月至 2020 年 6 月。
共确定了 106 篇文章，经过标题、摘要和全文筛选后，共纳入 12 篇全文。这涉及到 9299 名接受原发性 GI 手术的患者。在平均 5.4 年（范围：1-14.4 年）的随访期间，819 名（8.8%）患者发生了 KSD，各研究的发生率为 1.2%至 83%不等。结石形成的平均时间约为 3 年（范围：0.5-9 年）。在 4 项报告 KSD 管理情况的研究（n=427）中，38.6%的患者接受了泌尿外科干预。原发性 GI 手术后 KSD 的发生率很高，平均随访 3 年后，约 9%的患者发生了 KSD。尽管 GI 手术是为肥胖、炎症性肠病或癌症而做的，但在随访期间应牢记 KSD 的风险，并及时进行泌尿外科介入，进行代谢评估，提供药物和/或手术治疗。
