Concerto Carmen, Rodolico Alessandro, Mineo Ludovico, Ciancio Alessia, Marano Leonardo, Romano Carla Benedicta, Scavo Elisa Vita, Spigarelli Riccardo, Fusar-Poli Laura, Furnari Rosaria, Petralia Antonino, Signorelli Maria Salvina
Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
J Clin Med. 2023 Jun 16;12(12):4090. doi: 10.3390/jcm12124090.
Recovery is a broadly debated concept in the field of psychiatry research and in schizophrenia. Our study aims to understand the correlation between personal recovery from schizophrenia and factors such as mentalization, disability, quality of life, and antipsychotic side effects; Methods: Participants with schizophrenia (according to DSM-5 criteria) were consecutively recruited from the Psychiatry Unit of the University of Catania, Italy. Participants were assessed with the Recovery Assessment Scale (RAS), the Multidimensional Mentalizing Questionnaire (MMQ), the brief version of the WHO Disability Assessment Schedule (WHO-DAS), the EuroQoL-5 dimensions-5 levels, the Insight Orientation Scale (IOS) and the Glasgow Antipsychotic Side Effect Scale (GASS); Results: 81 patients were included. Our findings showed a positive correlation between RAS total scores and MMQ scores, especially in "good mentalizing" subdomains. IOS scores also had a positive association with RAS and MMQ scores. In contrast, poor mentalizing abilities negatively correlated with WHO-DAS 2.0 scores. While antipsychotic side effects influenced functioning, they did not impact perceived recovery. Conclusions: The study's results identified potential predictors of personal recovery from schizophrenia. These findings could contribute to creating tailored interventions to facilitate the recovery process.
康复是精神病学研究领域以及精神分裂症研究中一个广受争议的概念。我们的研究旨在了解精神分裂症患者的个人康复与诸如心理化、残疾、生活质量和抗精神病药物副作用等因素之间的相关性;方法:根据《精神疾病诊断与统计手册》第五版(DSM - 5)标准,从意大利卡塔尼亚大学精神病科连续招募精神分裂症患者。使用康复评估量表(RAS)、多维心理化问卷(MMQ)、世界卫生组织残疾评估量表简版(WHO - DAS)、欧洲五维健康量表(EuroQoL - 5维度 - 5水平)、领悟取向量表(IOS)和格拉斯哥抗精神病药物副作用量表(GASS)对参与者进行评估;结果:纳入81名患者。我们的研究结果显示RAS总分与MMQ得分之间呈正相关,尤其是在“良好心理化”子领域。IOS得分也与RAS和MMQ得分呈正相关。相比之下,心理化能力差与WHO - DAS 2.0得分呈负相关。虽然抗精神病药物副作用影响功能,但并未影响感知到的康复。结论:该研究结果确定了精神分裂症患者个人康复的潜在预测因素。这些发现有助于制定针对性的干预措施,以促进康复进程。