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精神痛苦与精神障碍患者的思维游荡、自我反思及洞察力的相关性:一项横断面研究

Mental Pain Correlates with Mind Wandering, Self-Reflection, and Insight in Individuals with Psychotic Disorders: A Cross-Sectional Study.

作者信息

Rodolico Alessandro, Cutrufelli Pierfelice, Brondino Natascia, Caponnetto Pasquale, Catania Gaetano, Concerto Carmen, Fusar-Poli Laura, Mineo Ludovico, Sturiale Serena, Signorelli Maria Salvina, Petralia Antonino

机构信息

Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.

Department of Brain and Behavioral Sciences, University of Pavia, Via Agostino Bassi 21, 27100 Pavia, Italy.

出版信息

Brain Sci. 2023 Nov 7;13(11):1557. doi: 10.3390/brainsci13111557.

Abstract

Understanding the cognitive processes that contribute to mental pain in individuals with psychotic disorders is important for refining therapeutic strategies and improving patient outcomes. This study investigated the potential relationship between mental pain, mind wandering, and self-reflection and insight in individuals diagnosed with psychotic disorders. We included individuals diagnosed with a 'schizophrenia spectrum disorder' according to DSM-5 criteria. Patients in the study were between 18 and 65 years old, clinically stable, and able to provide informed consent. A total of 34 participants, comprising 25 males and 9 females with an average age of 41.5 years (SD 11.5) were evaluated. The Psychache Scale (PAS), the Mind Wandering Deliberate and Spontaneous Scale (MWDS), and the Self-Reflection and Insight Scale (SRIS) were administered. Statistical analyses involved Spearman's rho correlations, controlled for potential confounders with partial correlations, and mediation and moderation analyses to understand the indirect effects of MWDS and SRIS on PAS and their potential interplay. Key findings revealed direct correlations between PAS and MWDS and inverse correlations between PAS and SRIS. The mediation effects on the relationship between the predictors and PAS ranged from 9.22% to 49.8%. The largest statistically significant mediation effect was observed with the SRIS-I subscale, suggesting that the self-reflection and insight component may play a role in the impact of mind wandering on mental pain. No evidence was found to suggest that any of the variables could function as relationship moderators for PAS. The results underscore the likely benefits of interventions aimed at reducing mind wandering and enhancing self-reflection in psychotic patients (e.g., metacognitive therapy, mindfulness). Further research will be essential to elucidate the underlying mechanisms.

摘要

了解导致精神障碍患者心理痛苦的认知过程,对于完善治疗策略和改善患者预后至关重要。本研究调查了被诊断为精神障碍的个体中,心理痛苦、思维游荡以及自我反思与洞察力之间的潜在关系。我们纳入了根据《精神疾病诊断与统计手册》第5版标准被诊断为“精神分裂症谱系障碍”的个体。研究中的患者年龄在18至65岁之间,临床症状稳定,且能够提供知情同意书。总共评估了34名参与者,其中包括25名男性和9名女性,平均年龄为41.5岁(标准差11.5)。使用了心理痛苦量表(PAS)、思维游荡有意与自发量表(MWDS)以及自我反思与洞察力量表(SRIS)。统计分析包括斯皮尔曼等级相关分析,通过偏相关控制潜在混杂因素,以及中介和调节分析,以了解MWDS和SRIS对PAS的间接影响及其潜在相互作用。主要研究结果显示,PAS与MWDS之间存在直接相关性,PAS与SRIS之间存在负相关性。预测变量与PAS之间关系的中介效应范围为9.22%至49.8%。在SRIS - I子量表中观察到最大的具有统计学意义的中介效应,这表明自我反思与洞察力成分可能在思维游荡对心理痛苦的影响中发挥作用。没有证据表明任何变量可作为PAS的关系调节因子。研究结果强调了旨在减少精神疾病患者思维游荡和增强自我反思的干预措施(如元认知疗法、正念训练)可能带来的益处。进一步的研究对于阐明潜在机制至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6546/10670292/81dc0e4b6054/brainsci-13-01557-g001.jpg

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