Department of Medical Education, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Department of Medical Education, National Cheng Kung University Hospital, Tainan 704, Taiwan.
Medicina (Kaunas). 2023 May 24;59(6):1006. doi: 10.3390/medicina59061006.
Although cognitive-behavioral therapy is the first-line treatment for insomnia, pharmacotherapy is often prescribed to treat insomnia and related symptoms. In addition, muscle relaxants are commonly prescribed to alleviate muscle soreness when the pain is unbearable. However, pharmacotherapy can lead to numerous side effects. The non-drug strategy intravascular laser irradiation of blood (iPBM) has been advocated to improve pain, wound healing, blood circulation, and blood cell function to relieve insomnia and muscle soreness symptoms. Therefore, we assessed whether iPBM improves blood parameters and compared drug use before and after iPBM therapy.
Consecutive patients who received iPBM therapy between January 2013 and August 2021 were reviewed. The associations between laboratory data, pharmacotherapies, and iPBM therapy were retrospectively analyzed. We compared patient characteristics, blood parameters, and drug use within the three months before the first treatment and the three months after the last treatment. We also compared the changes before and after treatment in patients who received ≥10 or 1-9 iPBM treatments.
We assessed 183 eligible patients who received iPBM treatment. Of them, 18 patients reported insomnia disturbance, and 128 patients reported pain in any part of their body. After the treatment, HGB and HCT significantly increased after treatment in both the ≥10 and 1-9 iPBM treatment groups (HGB < 0.001 and = 0.046; HCT < 0.001 and = 0.029, respectively). Pharmacotherapy analysis revealed no significant differences in drug use before and after treatment, though drug use tended to decrease after iPBM.
iPBM therapy is an efficient, beneficial, and feasible treatment that increases HGB and HCT. While the results of this study do not support the suggestion that iPBM reduces drug use, further larger studies using symptom scales are needed to confirm the changes in insomnia and muscle soreness after iPBM treatment.
认知行为疗法是治疗失眠的首选方法,但药物治疗常常被用于治疗失眠及相关症状。此外,当疼痛难以忍受时,常开具肌肉松弛剂来缓解肌肉酸痛。然而,药物治疗会导致许多副作用。血管内激光照射血液(iPBM)的非药物策略已被提倡用于改善疼痛、伤口愈合、血液循环和血细胞功能,以缓解失眠和肌肉酸痛症状。因此,我们评估了 iPBM 是否能改善血液参数,并比较了 iPBM 治疗前后的药物使用情况。
回顾性分析了 2013 年 1 月至 2021 年 8 月期间接受 iPBM 治疗的连续患者。分析了实验室数据、药物治疗与 iPBM 治疗之间的关系。比较了首次治疗前三个月和最后一次治疗后三个月的患者特征、血液参数和药物使用情况。还比较了接受≥10 次或 1-9 次 iPBM 治疗的患者治疗前后的变化。
我们评估了 183 名接受 iPBM 治疗的合格患者。其中,18 名患者报告有失眠障碍,128 名患者报告身体任何部位有疼痛。治疗后,≥10 次和 1-9 次 iPBM 治疗组的 HGB 和 HCT 治疗后均显著增加(HGB < 0.001 和 = 0.046;HCT < 0.001 和 = 0.029)。药物治疗分析显示,治疗前后药物使用无显著差异,尽管 iPBM 后药物使用有减少趋势。
iPBM 治疗是一种有效、有益且可行的治疗方法,可增加 HGB 和 HCT。虽然本研究结果不支持 iPBM 减少药物使用的建议,但需要使用症状量表进行更大规模的研究来确认 iPBM 治疗后失眠和肌肉酸痛的变化。