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2018-2022 年罗马尼亚严重烧伤患者细菌感染的病因和多药耐药情况。

Etiology and Multi-Drug Resistant Profile of Bacterial Infections in Severe Burn Patients, Romania 2018-2022.

机构信息

Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Clinical Emergency Hospital of Plastic, Reconstructive Surgery and Burns, 010761 Bucharest, Romania.

出版信息

Medicina (Kaunas). 2023 Jun 14;59(6):1143. doi: 10.3390/medicina59061143.

Abstract

Infections in severe burns and their etiology are and will remain a big concern for the medical field. The multi-drug resistant strains of bacteria are a challenge of today's medicine. The aim of our study was to identify the etiological spectrum of bacterial infections in severe burn patients in Romania and their multi-drug resistant patterns. We performed a prospective study that included 202 adult patients admitted to the intensive care unit (ICU) of the Clinical Emergency Hospital of Plastic, Reconstructive Surgery and Burns, Bucharest, Romania (CEHPRSB), from 1 October 2018 to 1 April 2022, a period which includes the first 2 years of the outbreak of COVID-19. From each patient, wound swabs, endotracheal aspirates, blood for blood culture, and urine were collected. The most frequently isolated bacterium was (39%), followed by (12%), spp. (11%), and (9%). More than 90% of and were MDR, regardless of the clinical specimen from which they were isolated.

摘要

严重烧伤的感染及其病因一直是医学界关注的焦点。多重耐药菌是当今医学的挑战。我们的研究目的是确定罗马尼亚严重烧伤患者的细菌感染病因谱及其多药耐药模式。我们进行了一项前瞻性研究,纳入了 202 名 2018 年 10 月 1 日至 2022 年 4 月 1 日期间入住罗马尼亚布加勒斯特整形、重建和烧伤临床急救医院(CEHPRSB)重症监护病房(ICU)的成年患者,该期间包括 COVID-19 爆发的头 2 年。从每位患者采集伤口拭子、气管内抽吸物、血培养和尿液。最常分离的细菌是 (39%),其次是 (12%)、 spp.(11%)和 (9%)。超过 90%的 和 是 MDR,无论从哪种临床标本中分离出来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/851b/10305704/daa03d63ea5c/medicina-59-01143-g001.jpg

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