Liu Liming, Li Letian, Li Chunhua, Wang Haiyang, Zhang Xiufeng, Ren Qingdan, Zhang Heping, Jin Ningyi, Li Chang, Zhao Cuiqing
College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132101, China.
Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
Microorganisms. 2023 Jun 10;11(6):1549. doi: 10.3390/microorganisms11061549.
This study aimed to investigate the effects of LPJZ-658 on the production, meat quality, intestinal morphology, and cecal microbiota of broilers. White-feathered broilers (1 day old, n = 600) were randomly assigned to two groups and raised for six weeks. The individuals in the LPJZ-658 group were supplemented with 2.6 × 10 cfu/g LPJZ-658. The growth performance, meat quality, intestinal epithelium morphology, and cecal microbiota were observed. The results showed that the average daily gain, average daily feed intake, and feed conversion ratio of broilers in the LPJZ-658 group were significantly improved. In addition, the LPJZ-658 groups had a higher thigh muscle (TM) yield, TM color, TM, breast muscle (BM) pH, and BM color, while the BM cooking loss was significantly lower than the CON group. Moreover, supplementation with LPJZ-658 increased ileum and cecum length, duodenum and ileum villus height, and ileum villus height/crypt depth ratio. Furthermore, 16S rRNA sequencing revealed the dietary LPJZ-658 supplementation modulated the diversity and composition of cecal microflora. At the phylum level, the relative abundances of Proteobacteria, Actinobacteria, Verrucomicrobiota, and Acidobacteriota were significantly higher. In addition, LPJZ-658 substantially decreased the genus relative abundances of Streptococcus, Veillonella, Neisseria, and Haemophilus compared with the CON group and facilitated the growth and colonization of beneficial cecal bacteria, such as OBacteroides, Phascolarctobacterium, Bacillus, and Akkermansia. It was concluded that LPJZ-658 supplementation significantly increased growth production, improved meat quality and intestinal status, and modulated the intestinal microbiota in the broilers.
本研究旨在探讨LPJZ - 658对肉鸡生产性能、肉质、肠道形态和盲肠微生物群的影响。将白羽肉鸡（1日龄，n = 600）随机分为两组，饲养6周。LPJZ - 658组的个体补充2.6×10 cfu/g的LPJZ - 658。观察生长性能、肉质、肠上皮形态和盲肠微生物群。结果表明，LPJZ - 658组肉鸡的平均日增重、平均日采食量和饲料转化率显著提高。此外，LPJZ - 658组的大腿肌肉（TM）产量、TM颜色、TM、胸肌（BM）pH值和BM颜色较高，而BM蒸煮损失显著低于对照组。此外，补充LPJZ - 658增加了回肠和盲肠长度、十二指肠和回肠绒毛高度以及回肠绒毛高度/隐窝深度比。此外，16S rRNA测序显示，日粮中添加LPJZ - 658可调节盲肠微生物群的多样性和组成。在门水平上，变形菌门、放线菌门、疣微菌门和酸杆菌门的相对丰度显著更高。此外，与对照组相比，LPJZ - 658显著降低了链球菌属、韦荣球菌属、奈瑟菌属和嗜血杆菌属的属相对丰度，并促进了有益盲肠细菌（如拟杆菌属、考拉杆菌属、芽孢杆菌属和阿克曼氏菌属）的生长和定殖。得出的结论是，补充LPJZ - 658显著提高了肉鸡的生长性能，改善了肉质和肠道状况，并调节了肠道微生物群。
