Department of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA.
Nutrients. 2023 Jun 7;15(12):2664. doi: 10.3390/nu15122664.
There is a lack of research on the effects of cannabidiol (CBD) on health-related fitness, physical activity, cognitive health, psychological wellbeing, and concentrations of C-reactive protein (CRP) in healthy individuals. CBD has potential anti-inflammatory and neuroprotective effects.
This study aimed to investigate the effects of 8 weeks of CBD on the above-mentioned measures in healthy individuals. Forty-eight participants were randomized into two groups receiving either oral capsules of 50 mg of CBD or a calorie-matched placebo daily. Participants completed pre- and post-intervention assessments, including blood draws, body composition, fitness, physical activity, and self-reported surveys.
There were no significant differences between groups regarding body composition, aerobic fitness, muscular strength, physical activity, cognitive health, psychological wellbeing, and resting CRP concentrations. However, the placebo group experienced a decline in mean peak power and relative peak power compared to the CBD group.
The results suggest that 8 weeks of CBD supplementation may prevent declines in anaerobic fitness over time. However, long-term CBD supplementation may not be beneficial for altering measures of health-related fitness, mental health, and inflammation in healthy individuals.
目前关于大麻二酚（CBD）对健康相关体能、身体活动、认知健康、心理健康和 C 反应蛋白（CRP）浓度的影响的研究还很少。CBD 具有潜在的抗炎和神经保护作用。
本研究旨在调查 8 周 CBD 对健康个体上述指标的影响。48 名参与者随机分为两组，每天分别口服 50mg CBD 胶囊或热量匹配的安慰剂。参与者完成干预前后的评估，包括血液采集、身体成分、体能、身体活动和自我报告的调查。
两组在身体成分、有氧体能、肌肉力量、身体活动、认知健康、心理健康和静息 CRP 浓度方面均无显著差异。然而，与 CBD 组相比，安慰剂组的平均峰值功率和相对峰值功率下降。
结果表明，8 周的 CBD 补充可能有助于防止随着时间的推移无氧体能下降。然而，长期 CBD 补充可能对改变健康相关体能、心理健康和炎症标志物在健康个体中的作用没有益处。
