Serri Carla, Cruz-Maya Iriczalli, Bonadies Irene, Rassu Giovanna, Giunchedi Paolo, Gavini Elisabetta, Guarino Vincenzo
Department of Medicine, Surgery and Pharmacy, University of Sassari, Via Muroni 23/a, 07100 Sassari, Italy.
Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Mostra d'Oltremare Pad. 20, V.le J.F. Kennedy 54, 80125 Naples, Italy.
Pharmaceutics. 2023 Jun 15;15(6):1744. doi: 10.3390/pharmaceutics15061744.
In the last decade, significant advances in nanotechnologies, rising from increasing knowledge and refining of technical practices in green chemistry and bioengineering, enabled the design of innovative devices suitable for different biomedical applications. In particular, novel bio-sustainable methodologies are developing to fabricate drug delivery systems able to sagely mix properties of materials (i.e., biocompatibility, biodegradability) and bioactive molecules (i.e., bioavailability, selectivity, chemical stability), as a function of the current demands for the health market. The present work aims to provide an overview of recent developments in the bio-fabrication methods for designing innovative green platforms, emphasizing the relevant impact on current and future biomedical and pharmaceutical applications.
在过去十年中，随着绿色化学和生物工程领域知识的不断增加以及技术实践的完善，纳米技术取得了重大进展，从而能够设计出适用于不同生物医学应用的创新设备。特别是，新型生物可持续方法正在不断发展，以制造能够根据健康市场当前需求巧妙结合材料特性（即生物相容性、生物降解性）和生物活性分子（即生物利用度、选择性、化学稳定性）的药物递送系统。本工作旨在概述用于设计创新绿色平台的生物制造方法的最新进展，强调其对当前和未来生物医学及制药应用的相关影响。
