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[13 - 14周龄和26周龄的正常血压Wistar - Kyoto大鼠(WKY)和自发性高血压大鼠(SHR)应激诱导的血糖水平变化]

[Stress-induced changes in blood glucose level in normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) aged 13-14 and 26 weeks].

作者信息

Roske I, Oehme P, Hirsch K

出版信息

Pharmazie. 1986 May;41(5):343-5.

PMID:3737667
Abstract

In normotensive WKY-rats and spontaneously hypertensive rats relations were investigated between the general stress related behaviour of adaptation and the blood glucose level under fasting condition. In respect to the level of blood glucose differences were existent specifically depending on age and strain. Compared with WKY-rats, spontaneously hypertensive rats on the same age had shown a higher stress related increase of blood glucose level. Furthermore an age depending increase of blood glucose level was found in both SHR and WKY-rats. These differences depending on strain and age are discussed including the further results about the influence of peptides on catecholamins and blood pressure regulation.

摘要

在正常血压的WKY大鼠和自发性高血压大鼠中,研究了禁食条件下与一般应激相关的适应性行为和血糖水平之间的关系。就血糖水平而言,存在着具体取决于年龄和品系的差异。与WKY大鼠相比,相同年龄的自发性高血压大鼠表现出与应激相关的更高血糖水平升高。此外,在SHR和WKY大鼠中均发现血糖水平随年龄增加。讨论了这些取决于品系和年龄的差异,包括关于肽对儿茶酚胺和血压调节影响的进一步结果。

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