Harris Rebecca Arden
Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania.
AJPM Focus. 2023 Mar;2(1). doi: 10.1016/j.focus.2022.100063. Epub 2022 Dec 22.
Fatal drug overdoses have risen sharply in the U.S. since 2015, reaching their highest levels during the pandemic. Non-Hispanic Black men have been disproportionately harmed by this latest surge; overdose mortality per 100,000 has increased fourfold since 2015. Whether the mortality rate will continue to climb is unknown. In this study, we addressed the narrower question of which age groups are likely to experience a significant increase or decrease in the burden of drug overdose deaths through 2025, based on foreseeable changes in the age structure of the Black male population.
We used the 2020 and provisional 2021 age-specific mortality rates from the Centers for Disease Control WONDER (Wide-Ranging Online Data for Epidemiologic Research) database and the standard population balancing equation to project overdose deaths in 2025. Overdose deaths were identified by ICD-10 codes. We bracketed the projections between 2 plausible alternatives: a pessimistic forecast based on time series extrapolations and an optimistic forecast that assumes success nationally in lowering overdose deaths through prevention, treatment, and harm reduction initiatives.
Among Black men aged 31-47 years, overdose deaths in 2025 are expected to increase by 440 or 11% (95% CI=8%, 14%) relative to 2020. By contrast, overdose deaths among younger Black men aged 19-30 years are expected to decline by 160 or -9% (95% CI= -15%, -5%). Among older Black men aged 48-64 years, overdose deaths are also expected to decline by 330 or -7% (95% CI= -10%, -4%). Similar results were found using 2021 provisional mortality rates.
Overdose deaths are predicted to increase significantly over current levels among Black men in their 30s and 40s. Local policy makers should direct harm reduction resources, such as naloxone kits, syringes, and fentanyl test strips, to places frequented by Black men in this age group. Outreach messaging should be tailored to resonate with men of middle age. Equally urgent is the scaling up of nonstigmatizing, evidence-based drug treatment and recovery support services in Black neighborhoods.
自2015年以来,美国致命药物过量服用情况急剧上升,在疫情期间达到最高水平。非西班牙裔黑人男性受这一最新激增情况的影响尤为严重;自2015年以来,每10万人的过量服用死亡率增长了四倍。死亡率是否会继续攀升尚不清楚。在本研究中,基于黑人男性人口年龄结构的可预见变化,我们探讨了一个更狭义的问题,即到2025年哪些年龄组的药物过量死亡负担可能会显著增加或减少。
我们使用了疾病控制中心WONDER(广泛的在线流行病学研究数据)数据库中的2020年和2021年临时特定年龄死亡率以及标准人口平衡方程来预测2025年的过量服用死亡情况。通过ICD - 10编码确定过量服用死亡情况。我们在两种合理的替代方案之间进行预测:一种基于时间序列外推的悲观预测,以及一种乐观预测,即假设全国通过预防、治疗和减少伤害举措成功降低过量服用死亡情况。
预计到2025年,31至47岁的黑人男性过量服用死亡人数将比2020年增加440人,即增加11%(95%置信区间 = 8%,14%)。相比之下,预计19至30岁的年轻黑人男性过量服用死亡人数将减少160人,即减少 - 9%(95%置信区间 = - 15%, - 5%)。在48至64岁的老年黑人男性中,过量服用死亡人数预计也将减少330人,即减少 - 7%(95%置信区间 = - 10%, - 4%)。使用2021年临时死亡率也得出了类似结果。
预计30多岁和40多岁的黑人男性过量服用死亡人数将比当前水平显著增加。地方政策制定者应将减少伤害资源,如纳洛酮试剂盒、注射器和芬太尼检测试纸,导向这个年龄组黑人男性经常光顾的地方。外展信息应进行调整,以引起中年男性的共鸣。同样紧迫的是在黑人社区扩大无污名化、基于证据的药物治疗和康复支持服务。