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1999 年至 2019 年,55 岁及以上成年人因阿片类药物过量导致的死亡率存在性别、种族和民族差异。

Disparities by Sex and Race and Ethnicity in Death Rates Due to Opioid Overdose Among Adults 55 Years or Older, 1999 to 2019.

机构信息

Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Buehler Center for Health Policy and Economics, Northwestern University, Chicago, Illinois.

出版信息

JAMA Netw Open. 2022 Jan 4;5(1):e2142982. doi: 10.1001/jamanetworkopen.2021.42982.

DOI:10.1001/jamanetworkopen.2021.42982
PMID:35015062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8753495/
Abstract

IMPORTANCE

Rates of opioid overdose deaths are increasing for older adults. Less is known about these deaths compared with those of younger adults.

OBJECTIVE

To analyze rate variation among opioid overdose deaths in older adults by sex and by race and ethnicity over time.

DESIGN, SETTING, AND PARTICIPANTS: This 21-year longitudinal cross-sectional study of adults who died due to opioid overdose at 55 years or older stratified by sex and by race and ethnicity used data from the Multiple Cause of Death database from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research. The data include all opioid overdose deaths among this age group that occurred between January 1, 1999, and December 31, 2019 (N = 79 893).

EXPOSURES

Sex and racial and ethnic groups.

MAIN OUTCOMES AND MEASURES

Rates of opioid overdose deaths per 100 000 population by sex and by race and ethnicity for persons 55 years or older.

RESULTS

During the period 1999 to 2019, 79 893 US residents 55 years or older died due to an opioid overdose. Among these individuals, 79.97% were aged 55 to 64 years, and 58.98% were men. Annual numbers of deaths increased over time from 518 in 1999 to 10 292 in 2019. Annual rates of opioid overdose deaths per 100 000 persons 55 years or older increased over time and ranged from 0.90 in 1999 to 10.70 in 2019. Substantial variation by sex and by race and ethnicity was found. In 2013, rates among non-Hispanic Black men began to diverge from those of other demographic subgroups. By 2019, the opioid overdose fatality rate among non-Hispanic Black men 55 years or older was 40.03 per 100 000 population, 4 times greater than the overall opioid overdose fatality rate of 10.70 per 100 000 for persons of the same age.

CONCLUSIONS AND RELEVANCE

In this longitudinal cross-sectional study of US adults who died due to opioid overdose, the burden of opioid overdose deaths among older adults since 2013 was most concentrated among non-Hispanic Black men. Deaths among non-Hispanic Black men were disproportionality represented in the overall increase in the rate of opioid overdose deaths among older adults. Further research is needed to inform policy and practice.

摘要

重要性

阿片类药物过量死亡的发生率在老年人中正在上升。与年轻人相比,人们对这些死亡的了解较少。

目的

按性别和种族和民族分析老年阿片类药物过量死亡的发生率随时间的变化。

设计、地点和参与者:这项对 55 岁及以上因阿片类药物过量而死亡的成年人进行的 21 年纵向横断面研究,按性别和种族和民族进行分层,使用了疾病控制和预防中心广范围在线流行病学研究数据中的死亡原因数据库的数据。该数据包括该年龄段所有发生在 1999 年 1 月 1 日至 2019 年 12 月 31 日期间的阿片类药物过量死亡(N=79893)。

暴露因素

性别和种族和民族群体。

主要结果和措施

55 岁及以上人群中,每 10 万人因阿片类药物过量死亡的比率,按性别和种族和民族划分。

结果

在 1999 年至 2019 年期间,有 79893 名美国 55 岁及以上的居民死于阿片类药物过量。在这些人中,79.97%年龄在 55 至 64 岁之间,58.98%为男性。死亡人数逐年增加,从 1999 年的 518 人增加到 2019 年的 10292 人。每 10 万人 55 岁及以上的阿片类药物过量死亡比率随时间推移而上升,从 1999 年的 0.90 上升到 2019 年的 10.70。按性别和种族和民族发现了很大的差异。2013 年,非西班牙裔黑人男性的比率开始与其他人口亚组的比率不同。到 2019 年,55 岁及以上非西班牙裔黑人男性的阿片类药物过量死亡率为每 10 万人 40.03 人,是非西班牙裔白人中相同年龄人群总体阿片类药物过量死亡率 10.70 人的 4 倍。

结论和相关性

在这项对美国因阿片类药物过量而死亡的成年人进行的纵向横断面研究中,自 2013 年以来,老年阿片类药物过量死亡的负担主要集中在非西班牙裔黑人男性中。非西班牙裔黑人男性的死亡人数在老年人群中阿片类药物过量死亡比率的总体上升中不成比例地增加。需要进一步研究以制定政策和实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c422/8753495/8553adab0812/jamanetwopen-e2142982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c422/8753495/258adfca0132/jamanetwopen-e2142982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c422/8753495/8553adab0812/jamanetwopen-e2142982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c422/8753495/258adfca0132/jamanetwopen-e2142982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c422/8753495/8553adab0812/jamanetwopen-e2142982-g002.jpg

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