Dorow P
Arzneimittelforschung. 1978;28(5):853-6.
The effect of theophylline ethylenediamine oblong tablets (Euphyllin retard) was tested in 40 patients by means of a double-blind trial, applying a dose of 2 X 350 mg/d and 2 X 700 mg/d. At the dose of 2 X 700 mg/d Euphyllin retard showed a good bronchodilatory effect. A reduction of the obstruction in the airways and an improvement of the arterial blood gases was statistically secured. At the dose of 2 X 350 mg/d a sufficient bronchodilation could not be recorded.
通过双盲试验,对40名患者使用氨茶碱乙二胺长效片(优喘平)进行了疗效测试,给药剂量分别为每日2次,每次350毫克和每日2次,每次700毫克。在每日2次,每次700毫克的剂量下,优喘平显示出良好的支气管扩张作用。气道阻塞减轻以及动脉血气得到改善,这在统计学上得到了证实。在每日2次,每次350毫克的剂量下,未记录到充分的支气管扩张效果。