Dorow P
Arzneimittelforschung. 1978;28(5):853-6.
The effect of theophylline ethylenediamine oblong tablets (Euphyllin retard) was tested in 40 patients by means of a double-blind trial, applying a dose of 2 X 350 mg/d and 2 X 700 mg/d. At the dose of 2 X 700 mg/d Euphyllin retard showed a good bronchodilatory effect. A reduction of the obstruction in the airways and an improvement of the arterial blood gases was statistically secured. At the dose of 2 X 350 mg/d a sufficient bronchodilation could not be recorded.