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老年男性以男性乳腺增生为格雷夫斯病首发表现的罕见病例:一例报告

An Intriguing Case of Gynecomastia in an Elderly Male as the Initial Presentation of Graves' Disease: A Case Report.

作者信息

Sravya S L, Swain Jayshree, Lavanya Kasukurti, Teli Brij R, Jadhao Pooja A

机构信息

Endocrinology, Diabetes and Metabolism, Institute of Medical Sciences and SUM Hospital, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar, IND.

出版信息

Cureus. 2023 May 21;15(5):e39286. doi: 10.7759/cureus.39286. eCollection 2023 May.

DOI:10.7759/cureus.39286
PMID:37378148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10292151/
Abstract

Gynecomastia is the proliferation of fibroglandular tissue in the male breast due to an altered hormonal milieu between the inhibitory effect of androgens and the stimulatory effect of estrogens on the breast tissue causing feminization of the male breast. Physiological causes are more common along with a few pathological conditions leading to gynecomastia in the male population. Of these varied etiologies, thyrotoxicosis is one of the notable causes, though it is very rare in the elderly population. Gynecomastia as the initial presentation of Graves' disease that too in an elderly age group is very rare with very few cases reported in the literature. Here, we present a case of a 62-year-old male presenting with gynecomastia, who after a detailed evaluation, was diagnosed to have Graves' disease.

摘要

男性乳房肥大是指由于雄激素的抑制作用和雌激素对乳腺组织的刺激作用之间的激素环境改变,导致男性乳腺中纤维腺组织增生,从而引起男性乳房女性化。生理原因较为常见,同时也有一些病理状况会导致男性出现乳房肥大。在这些不同的病因中,甲状腺毒症是一个值得注意的原因,尽管在老年人群中非常罕见。以男性乳房肥大作为Graves病的初始表现,且发生在老年年龄组的情况极为罕见,文献中报道的病例很少。在此,我们报告一例62岁男性因乳房肥大就诊的病例,经过详细评估后,被诊断为Graves病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/ac0efdfc74ed/cureus-0015-00000039286-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/a3295bf55e90/cureus-0015-00000039286-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/f6e25a1d17e8/cureus-0015-00000039286-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/f52e45dd517d/cureus-0015-00000039286-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/78c82fadc7ad/cureus-0015-00000039286-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/ac0efdfc74ed/cureus-0015-00000039286-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/a3295bf55e90/cureus-0015-00000039286-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/f6e25a1d17e8/cureus-0015-00000039286-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/f52e45dd517d/cureus-0015-00000039286-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/78c82fadc7ad/cureus-0015-00000039286-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af3/10292151/ac0efdfc74ed/cureus-0015-00000039286-i05.jpg

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本文引用的文献

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Endocrinol Diabetes Metab Case Rep. 2021 Nov 1;2021. doi: 10.1530/EDM-20-0140.
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Gynecomastia as a presenting symptom of Graves' disease in a 49-year-old man.男性乳房发育作为一名49岁男性格雷夫斯病的首发症状。
Endocrinol Diabetes Metab Case Rep. 2021 Apr 1;2021. doi: 10.1530/EDM-20-0181.
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Unilateral gynecomastia and hypokalemic periodic paralysis as first manifestations of Graves' disease.单侧乳腺增生和低钾性周期性瘫痪是 Graves 病的首发表现。
Am J Med Sci. 2013 Jun;345(6):504-6. doi: 10.1097/MAJ.0b013e31827c9411.
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