Khoohaphatthanakul Somdul, Sriwijitkamol Apiradee
Danchang Hospital, Suphan Buri, Thailand.
Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Case Rep Endocrinol. 2016;2016:1946824. doi: 10.1155/2016/1946824. Epub 2016 Dec 1.
Graves' hyperthyroidism has a various number of well-recognized manifestations. Galactorrhea is a rare manifestation in this disease. We describe a 33-year-old man who presented with the symptoms of hyperthyroidism, gynaecomastia, and galactorrhea for 2 months. Physical examination revealed goitre, gynaecomastia, and galactorrhea, bilaterally. Laboratory investigations demonstrated high free thyroxine with suppressed thyroid-stimulating hormone level together with elevated anti-TSH receptor; therefore, the diagnosis of Graves' disease was confirmed. Other investigations to elucidate the etiology of galactorrhea were normal, so the galactorrhea was hypothesized to be caused by Graves' disease. The gynaecomastia and galactorrhea resolved with the successful treatment of hyperthyroidism. Although the galactorrhea is extremely rare in thyrotoxicosis male patients, to the best of our knowledge, this is the third case which reported gynaecomastia and galactorrhea in male patient who presented with thyrotoxicosis.
格雷夫斯病甲亢有多种公认的表现。溢乳是该疾病中一种罕见的表现。我们描述了一名33岁男性，他出现甲亢、男性乳房发育和溢乳症状2个月。体格检查发现双侧甲状腺肿大、男性乳房发育和溢乳。实验室检查显示游离甲状腺素升高，促甲状腺激素水平受抑制，同时抗促甲状腺激素受体升高；因此，格雷夫斯病的诊断得以证实。其他用于阐明溢乳病因的检查均正常，所以推测溢乳是由格雷夫斯病引起的。随着甲亢的成功治疗，男性乳房发育和溢乳症状得到缓解。尽管溢乳在男性甲状腺毒症患者中极为罕见，但据我们所知，这是第三例报道的伴有甲状腺毒症的男性患者出现男性乳房发育和溢乳的病例。
