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黏液性肾上腺皮质癌1例罕见病例

A Rare Case of Myxoid Adrenocortical Carcinoma.

作者信息

Ferrer Carmela Claire, Delos Reyes-Murillo Pamela R

机构信息

Pathology and Laboratory Medicine, National Kidney and Transplant Institute, Quezon City, PHL.

出版信息

Cureus. 2023 May 24;15(5):e39433. doi: 10.7759/cureus.39433. eCollection 2023 May.

Abstract

Myxoid adrenocortical carcinoma (myxoid ACC) is a rare subtype of adrenal cortical carcinoma with only a few cases reported in the literature. This tumor is characterized by small to large neoplastic cells in cords, diffuse sheets, or nodular architecture, which are surrounded by variable amounts of myxoid material. We are presented with an elderly female with a suprarenal mass which revealed a tumor composed of neoplastic cells surrounded by scant to abundant myxoid stroma. Expression for Melan-A, Inhibin, Synaptophysin, and Pancytokeratin, as well as a Ki-67 proliferative index of 15%, warrant a diagnosis of myxoid ACC.

摘要

黏液性肾上腺皮质癌(myxoid ACC)是肾上腺皮质癌的一种罕见亚型,文献中仅有少数病例报道。该肿瘤的特征是肿瘤细胞呈条索状、弥漫片状或结节状排列,大小不一,周围有数量不等的黏液样物质。我们收治了一名老年女性,其肾上腺有一肿块,病理显示肿瘤由被少量至大量黏液样基质包绕的肿瘤细胞组成。Melan-A、抑制素、突触素和全细胞角蛋白的表达,以及Ki-67增殖指数为15%,支持黏液性肾上腺皮质癌的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6af/10292038/77868fd00824/cureus-0015-00000039433-i01.jpg

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