Sannazzari G L, Gabriele P, Orecchia R, Fillini C, Melano A
Radiol Med. 1986 Jul-Aug;72(7-8):573-8.
The authors present their results with hyperthermic treatment (alone or associated with radiation therapy) on 43 patients (with a total of 57 sites) treated from september 1983 to august 1985. All patients had recurrent lesion of pretreated malignant tumors. Among these there were brest adenocarcinomas, squamous cell carcinomas of head and neck, melanomas and soft tissues sarcomas. The clinical protocol was: hyperthermia alone (43 degrees-45 degrees C during 30 minutes) twice weekly (for a total of 8-10 treatments) or hyperthermia plus radiation therapy (4 Gy/fraction) for a total of 6-8 seances. In summary the response rate (CR + PR) was 80.4% (RT + HT 90% - HT alone 67.5%); the complete response rate was 24.5%.
作者介绍了1983年9月至1985年8月期间对43例患者(共57个部位)进行热疗(单独或与放射治疗联合)的结果。所有患者均为经治疗的恶性肿瘤复发病变。其中包括乳腺腺癌、头颈部鳞状细胞癌、黑色素瘤和软组织肉瘤。临床方案为:单独热疗(43摄氏度至45摄氏度,持续30分钟),每周两次(共8至10次治疗),或热疗加放射治疗(4 Gy/分次),共6至8次疗程。总之,缓解率(完全缓解+部分缓解)为80.4%(放疗+热疗90% - 单独热疗67.5%);完全缓解率为24.5%。