Department of Public Health, Albert Szent-Györgyi Medical School, University of Szeged, 10 Dóm Square, Szeged, Hungary, 6720.
BMC Musculoskelet Disord. 2023 Jun 30;24(1):537. doi: 10.1186/s12891-023-06662-w.
Osteoarthritis (OA) is one of the primary causes of pain and disability worldwide leading to patients having some of the worst health-related quality of life (QOL). The purpose of our study was to investigate the progression of the generic and disease-specific QOL of osteoarthritic patients going through total hip or knee replacement surgery and the factors that might alter the effect of surgery on QOL.
A longitudinal study was performed based on data collected from 120 OA patients who filled in the short version of the WHO's generic measure of quality of life (WHOQOL-BREF) and the disease-specific Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before and after surgery.
Domains related to physical health status showed relatively lower scores in patients before surgery. Patients reported a significant increase of QOL after surgery in the WHOQOL-BREF physical domain, especially if they were from the younger group (< 65 years, p = 0.022) or had a manual job (p = 0.008). Disease-specific QOL outcome results indicate that overall patients gained significantly better QOL in all domains of the WOMAC score. Patients with hip OA seemed to have the most benefit of their operation as they reported better outcome in WOMAC pain (p = 0.019), stiffness (p = 0.010), physical function domains (p = 0.011) and total score (p = 0.007) compared to knee OA patients.
There was a statistically significant improvement in all domains concerning physical functions in the study population. Patients also reported significant improvement in the social relationship domain, which indicates that OA itself as well as its management might have a profound effect on patients' life beyond the reduction of their pain.
骨关节炎（OA）是全球范围内导致疼痛和残疾的主要原因之一，使患者的健康相关生活质量（QOL）处于最差水平。我们的研究目的是调查接受全髋关节或全膝关节置换术的 OA 患者的一般和特定疾病 QOL 的进展情况，以及可能改变手术对 QOL 影响的因素。
基于 120 名 OA 患者在手术前后填写的世界卫生组织通用健康生活质量量表（WHOQOL-BREF）和特定疾病的西安大略和麦克马斯特大学骨关节炎指数（WOMAC）简短版数据，进行了一项纵向研究。
术前患者的身体健康状况相关领域得分相对较低。患者在手术后的 WHOQOL-BREF 生理领域报告了生活质量的显著提高，尤其是如果他们属于年轻组（<65 岁，p=0.022）或从事体力劳动（p=0.008）。特定疾病的 QOL 结果表明，总体而言，所有患者在 WOMAC 评分的所有领域都获得了更好的 QOL。髋关节 OA 患者似乎从手术中获益最大，因为他们在 WOMAC 疼痛（p=0.019）、僵硬（p=0.010）、身体功能领域（p=0.011）和总分（p=0.007）方面的报告结果都更好。
在研究人群中，所有与身体功能相关的领域都有统计学上的显著改善。患者还报告了社会关系领域的显著改善，这表明 OA 及其管理除了减轻疼痛外，可能对患者的生活产生深远影响。
