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[冠心平对不稳定型心绞痛患者血小板动态功能及糖酵解与糖原分解各项指标的影响]

[Effect of corinfar on the dynamic function and various indices of glycolysis and glycogenolysis in the thrombocytes of patients with unstable stenocardia].

作者信息

Strizhak I G, Shanygina K I, Novikova N A, Chernysheva I N

出版信息

Ter Arkh. 1986;58(5):73-7.

PMID:3738797
Abstract

An increase in the aggregation properties of platelets accompanied by the activation of glycogenolysis and glycolysis was established in patients with unstable angina as compared to a control group of healthy persons. In most cases corinfar therapy resulted in a positive time course of the main platelet indices and a marked improvement of the patients' status. The correlation between the platelet aggregation index and phosphorylase A activity and their association with a course of disease indicated an opportunity of using these indices as accessory diagnostic criteria and control over therapeutic efficacy in unstable angina.

摘要

与健康对照组相比,不稳定型心绞痛患者血小板聚集特性增加,同时糖原分解和糖酵解激活。在大多数情况下,冠状动脉梗死治疗使主要血小板指标呈阳性病程,患者病情显著改善。血小板聚集指数与磷酸化酶A活性之间的相关性及其与疾病进程的关联表明,这些指标可作为辅助诊断标准,并用于监测不稳定型心绞痛的治疗效果。

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