Strizhak I G, Shanygina K I, Novikova N A, Chernysheva I N
Ter Arkh. 1986;58(5):73-7.
An increase in the aggregation properties of platelets accompanied by the activation of glycogenolysis and glycolysis was established in patients with unstable angina as compared to a control group of healthy persons. In most cases corinfar therapy resulted in a positive time course of the main platelet indices and a marked improvement of the patients' status. The correlation between the platelet aggregation index and phosphorylase A activity and their association with a course of disease indicated an opportunity of using these indices as accessory diagnostic criteria and control over therapeutic efficacy in unstable angina.
与健康对照组相比,不稳定型心绞痛患者血小板聚集特性增加,同时糖原分解和糖酵解激活。在大多数情况下,冠状动脉梗死治疗使主要血小板指标呈阳性病程,患者病情显著改善。血小板聚集指数与磷酸化酶A活性之间的相关性及其与疾病进程的关联表明,这些指标可作为辅助诊断标准,并用于监测不稳定型心绞痛的治疗效果。