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5-氯-2-甲基-4-异噻唑啉-3-酮（CMIT）控制飞机燃油系统微生物问题的机制。

Mechanism of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) in controlling microbial problems in aircraft fuel systems.

作者信息

Yan Xiaohan, Han Ruifang, Fan Weijie, Shan Borong, Yang Jie, Zhao Xiaodong

机构信息

School of Ocean, Yantai University Yantai 264005 China

Qingdao Campus of Naval Aeronautical University Qingdao 266041 China

出版信息

RSC Adv. 2023 Jun 28;13(28):19485-19494. doi: 10.1039/d3ra02970k. eCollection 2023 Jun 22.

DOI:10.1039/d3ra02970k
PMID:37388151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10301881/
Abstract

This research investigated the potential use of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) as a biocide in aircraft fuel systems, which is rarely studied due to the unique properties of such systems. The study assessed the effectiveness of CMIT against three microbial isolates using minimum inhibitory concentrations and bacteriostatic tests, and showed that CMIT had good activity against them. Electrochemical studies were conducted to determine the impact of CMIT on the 7B04 aluminum alloy, which demonstrated that CMIT acted as a cathodic inhibitor and exhibited certain levels of short-term and long-term corrosion inhibition effects at concentrations of 100 mg L and 60 mg L, respectively. Additionally, the research provided insights into the mechanisms governing microbial problems by studying the reaction of CMIT with glutathione and sulfate. Overall, the study suggested that CMIT may be a useful biocide in aircraft fuel systems and provided important information on its efficacy and mechanism of action.

摘要

本研究调查了5-氯-2-甲基-4-异噻唑啉-3-酮（CMIT）作为飞机燃油系统杀生剂的潜在用途，由于此类系统的独特性质，该用途鲜有研究。该研究使用最低抑菌浓度和抑菌试验评估了CMIT对三种微生物分离株的有效性，结果表明CMIT对它们具有良好的活性。进行了电化学研究以确定CMIT对7B04铝合金的影响，结果表明CMIT作为阴极缓蚀剂，在浓度分别为100 mg/L和60 mg/L时表现出一定程度的短期和长期缓蚀效果。此外，该研究通过研究CMIT与谷胱甘肽和硫酸盐的反应，深入了解了微生物问题的控制机制。总体而言，该研究表明CMIT可能是飞机燃油系统中一种有用的杀生剂，并提供了关于其功效和作用机制的重要信息。

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