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血管腔内修复术后破裂性腹主动脉瘤的死亡率及危险因素。

Mortality and risk factors for ruptured abdominal aortic aneurysm after repair endovascular (rARE).

作者信息

Jones Melissa, Faris Peter, Moore Randy

机构信息

Division of Vascular Surgery, Department of Surgery, Peter Lougheed Centre, Calgary, Alberta, Canada.

Department of Analytics, Alberta Health Services, Calgary, Alberta, Canada.

出版信息

J Vasc Surg Cases Innov Tech. 2023 Mar 28;9(3):101165. doi: 10.1016/j.jvscit.2023.101165. eCollection 2023 Sep.

Abstract

OBJECTIVE

The aim of this study was to characterize risk factors for infrarenal abdominal aortic aneurysm rupture after endovascular repair (rARE) and evaluate 30-day mortality in comparison to primary ruptured abdominal aortic aneurysm (rAAA).

METHODS

A retrospective review of all adult patients with rAAA at a single tertiary university care center between February 11, 2006, and December 31, 2018, was performed. A total of 267 patients with rAAA were identified, 11 of whom had rARE. Descriptive statistics were applied due to the small sample size.

RESULTS

Overall 30-day mortality was similar between primary rAAA and rARE (31.5% vs 27.3%); however, patients with rARE were more likely to receive palliative care (3.9% vs 18.2%). Mortality of patients who underwent operative intervention was 11.1% for rARE and 28.7% for primary rAAA at 30 days. All patients had an endoleak at the time of rupture. Type 1 and type 3 endoleaks resulting in direct aortic sac pressurization were the primary cause of rARE (9 of 11 patients); however, rupture occurred in two patients with only a type 2 endoleak. There was no sac expansion at the time of rupture in four of 11 patients with rARE. Four of 11 patients were lost to follow-up prior to rARE.

CONCLUSIONS

rARE is an uncommon complication following EVAR and contributes to late aneurysm-related mortality following endovascular repair. Although the 30-day mortality rate was similar for rARE and primary rAAA, larger series are required to determine which patients with rARE will benefit from intervention. The presence of endoleak and sac expansion may alert surgeons to increased risk of rARE; however, a subset of patients with rARE did not have sac expansion or surveillance imaging on follow-up. Loss to lifelong imaging surveillance remains a risk factor for rARE.

摘要

目的

本研究旨在明确血管腔内修复术后肾下腹主动脉瘤破裂(rARE)的危险因素,并评估与原发性破裂腹主动脉瘤(rAAA)相比的30天死亡率。

方法

对2006年2月11日至2018年12月31日期间在一家单一的三级大学医疗中心的所有成年rAAA患者进行回顾性研究。共识别出267例rAAA患者,其中11例发生了rARE。由于样本量小,采用描述性统计方法。

结果

原发性rAAA和rARE的总体30天死亡率相似(31.5%对27.3%);然而,rARE患者更有可能接受姑息治疗(3.9%对18.2%)。接受手术干预的患者在30天时,rARE的死亡率为11.1%,原发性rAAA为28.7%。所有患者在破裂时均存在内漏。导致主动脉瘤腔直接受压的1型和3型内漏是rARE的主要原因(11例患者中的9例);然而,有2例仅存在2型内漏的患者发生了破裂。11例rARE患者中有4例在破裂时瘤腔未扩张。11例患者中有4例在rARE之前失访。

结论

rARE是血管腔内修复术后一种罕见的并发症,并且是血管腔内修复术后晚期动脉瘤相关死亡的原因。虽然rARE和原发性rAAA的30天死亡率相似,但需要更大规模的系列研究来确定哪些rARE患者将从干预中获益。内漏和瘤腔扩张的存在可能提醒外科医生rARE风险增加;然而,一部分rARE患者在随访中没有瘤腔扩张或监测影像学检查。终身影像监测失访仍然是rARE的一个危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33e2/10300393/e5c522bc298f/gr1.jpg

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