Center for Medical Education in English, Poznan University of Medical Sciences, Poznan, Poland.
Postgrad Med J. 2023 Jun 30;99(1173):654-660. doi: 10.1136/postgradmedj-2022-141546. Epub 2022 Apr 4.
Antimicrobial resistance (AMR) problems cause an enormous challenge to our world in medicine and in agriculture and many other fields. The current situation makes bacteriophage therapy an attractive therapeutic candidate. Nevertheless, very limited clinical trials on bacteriophage therapy were performed and completed as of presence. Bacteriophage therapy alludes to infecting bacteria with a virus, this often results in a bactericidal effect. The compiled studies support the feasibility of treating AMR with bacteriophage. However, the efficacy of specific bacteriophage strains and the accurate dosage have to be further studied and tested rigorously.
抗微生物药物耐药性（AMR）问题在医学、农业和许多其他领域给我们的世界带来了巨大的挑战。目前的情况使得噬菌体治疗成为一种有吸引力的治疗候选方法。然而，截至目前，仅完成了非常有限的噬菌体治疗临床试验。噬菌体治疗是指用病毒感染细菌，这通常会导致杀菌作用。已汇编的研究支持使用噬菌体治疗 AMR 的可行性。然而，具体噬菌体菌株的疗效和准确剂量还需要进一步严格研究和测试。
