Primak R G, Lebed' O I
Ukr Biokhim Zh (1978). 1986 Jul-Aug;58(4):35-40.
Adsorption of phosphatidylcholine liposomes by montmorillonite was studied for its effect on peroxidation of phospholipids and structure of the bilayer. The UV spectroscopy has shown that adsorption decreases peroxidation of lipids. A parameter is suggested for estimating an oxidation degree of lipids at the stage of the intensive formation of secondary products of their peroxidation. Fluorescent probes (1-anilinonaphthalene-8-sulphonate and pyrene) are used to establish that structural changes of the bilayer take place in adsorbed liposomes being followed by a decrease in the mobility of surface zones of phospholipid "heads" and by an increase in the polarity of hydrophobic parts of the bilayer.
研究了蒙脱石对磷脂酰胆碱脂质体的吸附作用及其对磷脂过氧化和双层结构的影响。紫外光谱表明，吸附作用可降低脂质的过氧化。提出了一个参数，用于估计脂质过氧化二级产物大量形成阶段的脂质氧化程度。使用荧光探针（1-苯胺基萘-8-磺酸盐和芘）来确定吸附的脂质体中双层结构发生了变化，随后磷脂“头部”表面区域的流动性降低，双层疏水部分的极性增加。
