Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France; Educational and Research Institute, Barretos Cancer Hospital, Barretos, Brazil.
Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Cancer Epidemiol. 2023 Aug;85:102403. doi: 10.1016/j.canep.2023.102403. Epub 2023 Jun 28.
Cancer is a leading cause of morbidity and mortality in Brazil and the burden is rising. To better inform tailored cancer actions, we compare incidence and mortality profiles according to small areas in the capital and northeast region of the State of São Paulo for the leading cancer types.
New cancer cases were obtained from cancer registries covering the department of Barretos (2003-2017) and the municipality of São Paulo (2001-2015). Cancer deaths for the same period were obtained from a Brazilian public government database. Age-standardized rates per 100,000 persons-years by cancer and sex are presented as thematic maps, by municipality for Barretos region, and by district for São Paulo.
Prostate and breast cancer were the leading forms of cancer incidence in Barretos, with lung cancer leading in terms of cancer mortality in both regions. The highest incidence and mortality rates were seen in municipalities from the northeast of Barretos region in both sexes, while elevated incidence rates were mainly found in São Paulo districts with high and very high socioeconomic status (SES), with mortality rates more dispersed. Breast cancer incidence rates in São Paulo were 30 % higher than Barretos, notably in high and very high SES districts, while corresponding rates of cervical cancer conveyed the opposite profile, with elevated rates in low and medium SES districts.
There is substantial diversity in the cancer profiles in the two regions, by cancer type and sex, with a clear relation between the cancer incidence and mortality patterns observed at the district level and corresponding SES in the capital.
癌症是巴西发病率和死亡率的主要原因，且负担正在增加。为了更好地制定有针对性的癌症行动，我们根据巴西圣保罗州首府和东北部的小地区，比较了主要癌症类型的发病率和死亡率情况。
从覆盖巴雷托斯市（2003-2017 年）和圣保罗市（2001-2015 年）的癌症登记处获取新的癌症病例。同期的癌症死亡病例则从巴西公共政府数据库中获取。按癌症和性别，以每 10 万人年的年龄标准化率为单位，以市为单位呈现巴雷托斯地区的专题地图，以区为单位呈现圣保罗市的专题地图。
前列腺癌和乳腺癌是巴雷托斯地区发病率最高的癌症类型，而肺癌在两个地区的癌症死亡率中均处于领先地位。在两个地区的男性和女性中，巴雷托斯东北部的市的发病率和死亡率最高，而在圣保罗，高和极高社会经济地位（SES）的区的发病率较高，死亡率则分布较为分散。圣保罗的乳腺癌发病率比巴雷托斯高 30%，尤其是在高和极高 SES 区，而宫颈癌的相应发病率则呈现相反的模式，在低和中 SES 区发病率较高。
两个地区的癌症类型和性别存在显著差异，在首府，癌症发病率和死亡率模式与相应 SES 水平在区一级的分布存在明显关系。
