脑淀粉样血管病皮质浅表层铁沉积症的前驱症状和时间发展：病例报告。
Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report.
机构信息
Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
出版信息
BMC Neurol. 2023 Jun 30;23(1):252. doi: 10.1186/s12883-023-03300-9.
BACKGROUND
We present a case illustrating evolution of symptoms and brain magnetic resonance imaging in cortical superficial siderosis.
CASE PRESENTATION
A 74-year-old man with no prior medical history presented with transient focal neurological episodes with subtle imaging changes. There was no evidence of cortical superficial siderosis. Two weeks later, the patient was readmitted with new episodes, and had developed cortical superficial siderosis adjacent to a cerebral microbleed. Transient focal neurological episode secondary to cortical superficial siderosis was diagnosed together with probable cerebral amyloid angiopathy.
CONCLUSION
Clinical symptoms may precede the development of cortical superficial siderosis prior to being detectable on brain MRI. This case highlights the temporal development of cortical superficial siderosis.
背景
我们报告了一例皮质下铁沉积症的症状演变和脑部磁共振成像的病例。
病例介绍
一名 74 岁的男子，无既往病史，出现短暂性局灶性神经症状，影像学改变轻微。无皮质下铁沉积症的证据。两周后，患者因新发作再次入院，并在脑微出血旁出现皮质下铁沉积症。诊断为皮质下铁沉积症引起的短暂性局灶性神经症状，可能合并脑淀粉样血管病。
结论
在脑部 MRI 可检测到皮质下铁沉积症之前，临床症状可能先出现。本病例强调了皮质下铁沉积症的时间演变。
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