Chapman H D
Vet Parasitol. 1986 Jun;21(2):83-90. doi: 10.1016/0304-4017(86)90148-2.
Resistance to halofuginone has been developed by serially passaging the Houghton strain of Eimeria tenella in chickens medicated with progressively greater concentrations of drug. Attempts to develop resistance to 3 ppm (as recommended for use by the manufacturer) or higher concentrations, by the method of Weppelman et al., were unsuccessful.
通过在用药浓度逐渐增加的鸡群中连续传代柔嫩艾美耳球虫霍顿株,已培育出对常山酮具有抗性的虫株。按照韦佩尔曼等人的方法,尝试培育对3 ppm(制造商推荐的使用浓度)或更高浓度常山酮具有抗性的虫株,但未成功。