托曲珠利和常山酮对埃及肉鸡柔嫩艾美耳球虫感染的抗球虫效果

Anticoccidial efficacy of toltrazuril and halofuginone against Eimeria tenella infection in broiler chickens in Egypt.

作者信息

Ramadan A, Abo el-Sooud K, el-Bahy M M

机构信息

Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

出版信息

Res Vet Sci. 1997 Mar-Apr;62(2):175-8. doi: 10.1016/s0034-5288(97)90142-9.

DOI:10.1016/s0034-5288(97)90142-9

PMID:9243719

Abstract

The anticoccidial activities of toltrazuril and halofuginone against Eimeria tenella were tested in broiler chickens. Comparisons were made between ummedicated infected and uninfected control birds in addition to infected groups given either toltrazuril at 37.5, 75 and 150 ppm in the drinking water, or halofuginone at 1.5, 3 and 6 ppm in the feed. Both drugs were highly efficacious against E tenella. Treatment improved the bodyweight gain and survival percentage in comparison with the unmedicated, infected group. Intestinal lesions, faecal and oocyst scores and oocyst shedding in dropping were significantly reduced by both drugs. Toltrazuril gave better protection than halofuginone; 75 and 150 ppm toltrazuril in drinking water gave good protection when administered four and five days after inoculation.

摘要

在肉鸡中测试了托曲珠利和常山酮对柔嫩艾美耳球虫的抗球虫活性。除了未用药的感染鸡和未感染的对照鸡外，还对饮水中添加37.5、75和150 ppm托曲珠利或饲料中添加1.5、3和6 ppm常山酮的感染组进行了比较。两种药物对柔嫩艾美耳球虫均具有高效。与未用药的感染组相比，治疗提高了体重增加和存活率。两种药物均显著降低了肠道病变、粪便和卵囊评分以及粪便中的卵囊排出量。托曲珠利的保护效果优于常山酮；接种后第4天和第5天饮用含75和150 ppm托曲珠利的饮水可提供良好的保护。