Sengar D P, Rashid A, Harris J E
Clin Exp Immunol. 1979 Feb;35(2):236-41.
Active T(AT) and EA-rosette-forming cells (RFC) were determined in seventeen haemodialysis patients and twenty-two renal allograft recipients to correlate these estimates with the clinical outcome of renal allografts. Either AT- or EA-RFC or both were found to be elevated during the period of rejection crisis. Assays for AT- and EA-RFC were found to be complementary suggesting that they may be detecting two different types of rejection crises. Thus, determination of AT- and EA-RFC in the peripheral blood may prove to be useful in the routine immunological monitoring of renal allograft recipients.
对17名血液透析患者和22名肾移植受者测定了活性T细胞(AT)和Ea玫瑰花结形成细胞(RFC),以将这些评估结果与肾移植的临床结果相关联。在排斥反应危机期间,发现AT或Ea - RFC或两者均升高。发现AT和Ea - RFC检测具有互补性,表明它们可能检测到两种不同类型的排斥反应危机。因此,测定外周血中的AT和Ea - RFC可能在肾移植受者的常规免疫监测中被证明是有用的。