ARC Centre of Excellence for Nanoscale Biophotonics, Macquarie University, Sydney, NSW, Australia; School of Natural Sciences, Macquarie University, Sydney, NSW, Australia; ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, Australia.
ARC Centre of Excellence for Nanoscale Biophotonics, Macquarie University, Sydney, NSW, Australia; School of Natural Sciences, Macquarie University, Sydney, NSW, Australia.
Brain Behav Immun. 2023 Oct;113:83-90. doi: 10.1016/j.bbi.2023.06.024. Epub 2023 Jun 30.
The Allen Institute Mouse Brain Atlas, with visualisation using the Brain Explorer software, offers a 3-dimensional view of region-specific RNA expression of thousands of mouse genes. In this Viewpoint, we focused on the region-specific expression of genes related to cellular glycosylation, and discuss their relevance towards psychoneuroimmunology. Using specific examples, we show that the Atlas validates existing observations reported by others, identifies previously unknown potential region-specific glycan features, and highlights the need to promote collaborations between glycobiology and psychoneuroimmunology researchers.
艾伦脑科学研究所的老鼠大脑图谱，通过 Brain Explorer 软件进行可视化，提供了数千个老鼠基因的区域特异性 RNA 表达的三维视图。在本观点中，我们专注于与细胞糖基化相关的基因的区域特异性表达，并讨论它们与心理神经免疫学的相关性。通过具体的例子，我们表明图谱验证了其他人报告的现有观察结果，确定了以前未知的潜在区域特异性聚糖特征，并强调了促进糖生物学和心理神经免疫学研究人员之间合作的必要性。
