Division of Pediatric Infectious Diseases.
School of Medicine, Duke University, Durham, North Carolina.
Pediatrics. 2023 Jul 1;152(Suppl 1). doi: 10.1542/peds.2022-060352I.
The Centers for Disease Control and Prevention recommend that schools can offer severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic (on-demand) testing for students and staff with coronavirus disease 2019 symptoms or exposures. Data related to the uptake, implementation, and effect of school-associated on-demand diagnostic testing have not been described.
The Rapid Acceleration of Diagnostics Underserved Populations Return to School program provided resources to researchers to implement on-demand SARS-CoV-2 testing in schools. This study describes the strategies used and uptake among the different testing programs. Risk of positivity was compared for symptomatic and exposure testing during the δ and ο variant periods. We estimated the number of school absence days saved with school-based diagnostic testing.
Of the 16 eligible programs, 7 provided school-based on-demand testing. The number of persons that participated in these testing programs is 8281, with 4134 (49.9%) receiving >1 test during the school year. Risk of positivity was higher for symptomatic testing compared with exposure testing and higher during the ο variant predominant period compared with the δ variant predominant period. Overall, access to testing saved an estimated 13 806 absent school days.
School-based on-demand SARS-CoV-2 testing was used throughout the school year, and nearly half the participants accessed testing on more than 1 occasion. Future studies should work to understand participant preferences around school-based testing and how these strategies can be used both during and outside of pandemics.
疾病控制与预防中心建议学校可为出现 2019 冠状病毒病症状或暴露于 2019 冠状病毒病的学生和教职员工提供严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)诊断(按需)检测。目前尚未描述与学校相关的按需诊断检测的采用、实施和效果相关的数据。
快速加速诊断弱势人群返校计划为研究人员提供资源,以在学校实施按需 SARS-CoV-2 检测。本研究描述了不同检测项目中使用的策略和采用情况。比较了在 δ 和 ο 变异期间,有症状和暴露检测的阳性风险。我们估计了通过基于学校的诊断检测可以节省多少天的缺课。
在 16 个符合条件的项目中,有 7 个提供了基于学校的按需检测。这些检测项目共涉及 8281 人,其中 4134 人(49.9%)在整个学年中接受了超过 1 次检测。与暴露检测相比,有症状检测的阳性风险更高,与 δ 变异为主的时期相比,ο 变异为主的时期阳性风险更高。总体而言,检测的普及估计节省了 13806 天的缺课。
整个学年都在学校开展了按需 SARS-CoV-2 检测,近一半的参与者接受了 1 次以上的检测。未来的研究应致力于了解参与者对基于学校的检测的偏好,以及这些策略如何在大流行期间和之外使用。