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[缓慢进行性疑病型精神分裂症的心理药物治疗]

[Psychopharmacotherapy of slowly progressive hypochondriacal schizophrenia].

作者信息

Smulevich A B, Basov A M, Dubnitskaia E B, Izmaĭlova L G

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(11):1583-7.

PMID:42244
Abstract

The efficacy of psychopharmacological treatment modalities and comatose methods was studied in the therapy of patients with slowly progressive schizophrenia, the clinical picture of which was characterized by cenestho-hypochondriacal disturbances (155 cases). The use of high doses of neuroleptics, atropine and insulin comas in these cases were ineffective. A positive compliance to therapy was attained in the treatment by tranquilizers of the benzodiazepine series, especially by a parenteral administration. The best results were demonstrated in the treatment of pseudoneurotic hypochondria. The therapeutic reluctancy increased in the cenestho-algic syndrome and in the syndrome of "rigid" hypochondria. The most effective in these cases was a combined therapy by tranquilizers (parenteral administration) and small doses of neuroleptics.

摘要

对缓慢进展型精神分裂症患者(155例)进行治疗时,研究了精神药物治疗方式和昏迷疗法的疗效,其临床症状以体感-疑病障碍为特征。在这些病例中,使用高剂量抗精神病药物、阿托品和胰岛素昏迷疗法均无效。采用苯二氮䓬类镇静剂治疗,尤其是采用胃肠外给药时,治疗依从性良好。在假性神经症性疑病症的治疗中取得了最佳效果。在体感疼痛综合征和“僵硬”疑病症综合征中,治疗抵触情绪增加。在这些病例中,最有效的是镇静剂(胃肠外给药)和小剂量抗精神病药物联合治疗。

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