Smulevich A B, Basov A M, Dubnitskaia E B, Izmaĭlova L G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(11):1583-7.
The efficacy of psychopharmacological treatment modalities and comatose methods was studied in the therapy of patients with slowly progressive schizophrenia, the clinical picture of which was characterized by cenestho-hypochondriacal disturbances (155 cases). The use of high doses of neuroleptics, atropine and insulin comas in these cases were ineffective. A positive compliance to therapy was attained in the treatment by tranquilizers of the benzodiazepine series, especially by a parenteral administration. The best results were demonstrated in the treatment of pseudoneurotic hypochondria. The therapeutic reluctancy increased in the cenestho-algic syndrome and in the syndrome of "rigid" hypochondria. The most effective in these cases was a combined therapy by tranquilizers (parenteral administration) and small doses of neuroleptics.
对缓慢进展型精神分裂症患者(155例)进行治疗时,研究了精神药物治疗方式和昏迷疗法的疗效,其临床症状以体感-疑病障碍为特征。在这些病例中,使用高剂量抗精神病药物、阿托品和胰岛素昏迷疗法均无效。采用苯二氮䓬类镇静剂治疗,尤其是采用胃肠外给药时,治疗依从性良好。在假性神经症性疑病症的治疗中取得了最佳效果。在体感疼痛综合征和“僵硬”疑病症综合征中,治疗抵触情绪增加。在这些病例中,最有效的是镇静剂(胃肠外给药)和小剂量抗精神病药物联合治疗。