Schoenberger J A
Clin Pharmacol Ther. 1979 May;25(5 Pt 2):681-4. doi: 10.1002/cpt1979255part2681.
Both the Coronary Drug Project (CDP) and the Aspirin Myocardial Infarction Study (AMIS) were successfully able to recruit adequate members of postmyocardial infarction patients to long-term multicenter clinical trials in the secondary prevention of coronary heart disease. Aggressive efforts to achieve the recruitment within an acceptable time limit were found to be neccessary. A direct approach to the general public via the mass media and painstaking search of hospital records proved to be the most effective methods. Referral from physicians was not an effective way to recruit participants for the most part. Both the general public and the medical profession are generally supportive of this type of research.
冠心病药物研究项目（CDP）和阿司匹林心肌梗死研究（AMIS）都成功招募到了足够数量的心肌梗死后患者，以开展冠心病二级预防的长期多中心临床试验。人们发现，有必要在可接受的时间限制内积极努力以实现招募目标。事实证明，通过大众媒体直接面向公众以及精心查阅医院记录是最有效的方法。在很大程度上，医生转诊并不是招募参与者的有效方式。一般公众和医学界总体上都支持这类研究。
