Lipids. 1977 Jan;12(1):59-63. doi: 10.1007/BF02532973.
The Aspirin Myocaridal Infarction Study is a randomized, double-blind clinical trial designed to study the potential value of aspirin in the reduction of mortality in patients who have had a prior myocardial infarction. This trial is based upon several previously published studies which suggest that aspirin may be valuable iprevention of coronary thrombosis. The requirement of 4200 patients dictates that the study must be multicenter, and good design requires that the study be collaborative with cnetral monitoring and an elaborate committee structure to insure uniformity and comparability.
阿司匹林心肌梗死研究是一项随机、双盲临床试验，旨在研究阿司匹林在降低既往有心肌梗死患者死亡率方面的潜在价值。该试验基于此前发表的多项研究，这些研究表明阿司匹林在预防冠状动脉血栓形成方面可能具有价值。招募4200名患者的要求决定了该研究必须是多中心的，而良好的设计要求该研究与中央监测协作，并建立一个精心设计的委员会结构，以确保一致性和可比性。
