An intervention study-the aspirin myocardial infarction study.

The Aspirin Myocaridal Infarction Study is a randomized, double-blind clinical trial designed to study the potential value of aspirin in the reduction of mortality in patients who have had a prior myocardial infarction. This trial is based upon several previously published studies which suggest that aspirin may be valuable iprevention of coronary thrombosis. The requirement of 4200 patients dictates that the study must be multicenter, and good design requires that the study be collaborative with cnetral monitoring and an elaborate committee structure to insure uniformity and comparability.