Qu Shanlin, Yu Shuo, Ma Xiaolin, Wang Rui
Hospital of Stomatology, Jilin University, Changchun, China.
Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun, China.
Front Nutr. 2023 Jun 15;10:1193289. doi: 10.3389/fnut.2023.1193289. eCollection 2023.
"Medicine food homology" (MFH) is a term with a lengthy history. It refers to the fact that a lot of traditional natural products have both culinary and therapeutic benefits. The antibacterial, anti-inflammatory and anticancer effects of MFH plants and their secondary metabolites have been confirmed by numerous research. A bacterially generated inflammatory illness with a complicated pathophysiology, periodontitis causes the loss of the teeth's supporting tissues. Several MFH plants have recently been shown to have the ability to prevent and treat periodontitis, which is exhibited by blocking the disease's pathogens and the virulence factors that go along with them, lowering the host's inflammatory reactions and halting the loss of alveolar bone. To give a theoretical foundation for the creation of functional foods, oral care products and adjuvant therapies, this review has especially explored the potential medicinal benefit of MFH plants and their secondary metabolites in the prevention and treatment of periodontitis.
“药食同源”有着悠久的历史。它指的是许多传统天然产物兼具烹饪和治疗功效。众多研究已证实药食同源植物及其次生代谢产物的抗菌、抗炎和抗癌作用。牙周炎是一种具有复杂病理生理学的细菌性炎症性疾病，会导致牙齿支持组织丧失。最近有研究表明，几种药食同源植物能够预防和治疗牙周炎，其作用表现为阻断该疾病的病原体及其相关毒力因子，降低宿主的炎症反应并阻止牙槽骨丧失。为了给功能性食品、口腔护理产品和辅助治疗的开发提供理论基础，本综述特别探讨了药食同源植物及其次生代谢产物在预防和治疗牙周炎方面的潜在药用价值。
