Lotz P, Posse D, Haberland E J, Kuhl K D, Ernst A
Acta Otolaryngol. 1986 Jul-Aug;102(1-2):20-6. doi: 10.3109/00016488609108641.
Guinea pigs were exposed to continuous white noise of 120 dB SPL. The performance included a recording of CM, pO2, and metabolites in the perfusate of the perilymphatic spaces. The metabolic reactions observed following the exposure are limited. No evidence of an overstimulation or of an insufficiency of the energy metabolism in the cochlea could be found. The results suggest the metabolic processes to be secondary to the sound-dependent damage of the organ of Corti after irreversible mechanical destructions in the hair cells.
将豚鼠暴露于120 dB SPL的连续白噪声中。实验操作包括记录耳蜗微音器电位（CM）、氧分压（pO2）以及外淋巴间隙灌流液中的代谢物。暴露后观察到的代谢反应有限。未发现耳蜗存在过度刺激或能量代谢不足的证据。结果表明，在毛细胞发生不可逆的机械性破坏后，代谢过程继发于依赖声音的柯蒂氏器损伤。
