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大鼠反应抑制条件性抑制剂的泛化

Generalization of a conditioned inhibitor of response suppression in rats.

作者信息

Wesierska M, Brennan J F, Zieliński K

出版信息

Acta Neurobiol Exp (Wars). 1986;46(1):11-26.

PMID:3739758
Abstract

Following acquisition of conditioned suppression of barpresses to a visual conditiondd stimulus (CS), rats were subjected to a particular variety of differentiation training procedures. An auditory conditioned inhibitor (CI), which preceded and accompanied the CS on some trials, signaled that inescapable shock will not be given on that trial. When the CI acquired the capacity to attenuate markedly the suppressive effects of the CS presented within the CI + CS compound, the frequency dimension of the CI was varied during generalization tests. Reliable within-subjects gradients of barpress enhancement were obtained when tone test frequencies were presented alone. Frequency gradients obtained from CI variation in compound with the CS were rather flat and reflected some residual suppression of the on-going barpressing.

摘要

在获得对视觉条件刺激(CS)的压杆条件性抑制后,对大鼠进行了特定种类的辨别训练程序。一种听觉条件性抑制剂(CI),在某些试验中先于并伴随CS出现,表明该试验不会给予不可逃避的电击。当CI获得显著减弱CI + CS复合刺激中呈现的CS的抑制作用的能力时,在泛化测试中改变CI的频率维度。当单独呈现纯音测试频率时,获得了可靠的受试者内压杆增强梯度。从与CS复合的CI变化中获得的频率梯度相当平坦,反映了对正在进行的压杆的一些残余抑制。

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