State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
Chem Commun (Camb). 2023 Jul 18;59(58):8993-8996. doi: 10.1039/d3cc02430j.
The atom transfer radical cyclisation of unactivated alkyl bromides was realized by using a catalytic system of CuBr and Me-TREN. This protocol is applicable to the preparation of five-membered rings from unsaturated primary and secondary bromides.
通过使用 CuBr 和 Me-TREN 的催化体系，实现了未活化的烷基溴化物的原子转移自由基环化反应。该方案适用于从不饱和伯溴化物和仲溴化物制备五元环。
