通过光氧化还原/铜催化体系实现氟烷基溴化物与烯烃的原子转移自由基加成反应。
Atom-transfer radical addition of fluoroalkyl bromides to alkenes via a photoredox/copper catalytic system.
作者信息
Kostromitin Vladislav S, Zemtsov Artem A, Kokorekin Vladimir A, Levin Vitalij V, Dilman Alexander D
机构信息
N. D. Zelinsky Institute of Organic Chemistry, Moscow 119991, Leninsky prosp. 47, Russian Federation and Lomonosov Moscow State University, Department of Chemistry, Moscow 119991, Leninskie Gory 1-3, Russian Federation.
N. D. Zelinsky Institute of Organic Chemistry, Moscow 119991, Leninsky prosp. 47, Russian Federation.
出版信息
Chem Commun (Camb). 2021 May 25;57(42):5219-5222. doi: 10.1039/d1cc01609a. Epub 2021 Apr 28.
A method for the addition of fluorinated alkyl bromides to alkenes is described. The reaction proceeds under visible light irradiation in the presence of two catalysts: Ir(ppy) and N-heterocyclic carbene ligated copper bromide (IMesCuBr). The role of the iridium photocatalyst is to generate the fluoralkyl radical, while the copper promotes formation of the carbon-bromine bond.
描述了一种将氟化烷基溴加成到烯烃上的方法。该反应在可见光照射下，在两种催化剂存在的情况下进行：铱（ppy）和氮杂环卡宾配位的溴化铜（IMesCuBr）。铱光催化剂的作用是生成氟烷基自由基，而铜则促进碳-溴键的形成。
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