Dermatology and Allergy Department, Médecine Sorbonne Université, Service de dermatologie et d'allergologie, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris (AP-HP), Tenon Hospital, AP-HP, Paris, France.
Department of Dermatology and Allergology, INSERM, Institut Pierre Louis d'Epidemiologie et de Sante Publique, AP-HP Sorbonne Universite, Tenon Hopital, Paris, France.
Contact Dermatitis. 2023 Sep;89(3):190-197. doi: 10.1111/cod.14377. Epub 2023 Jul 4.
To analyse the clinical characteristics and sensitivity of an essential oil patch test series (EOS) in patients sensitized to their own essential oils (EOs).
We analysed the clinical data and patch test results obtained with the European baseline series (BSE) and an EOS, as well as the mode of use of EOs, through a questionnaire included in the patient file.
The study included 42 patients (79% women, average age 50 years) with allergic contact dermatitis (ACD), 8 patients required hospitalization. All patients were sensitized to the EO they used, primarily lavender (Lavandula augustifolia, 8000-28-0), tea tree (Melaleuca alternifolia leaf oil, 68647-73-4), ravintsara (Cinnamomum camphora oil, 92201-50-8), and 2 cases were attributed to helichrysum (helichrysum italicum flower absolute, 90045-56-0). 71% had positive patch tests to fragrance mix I or II, 9 only to the EOS and 4 only with their personal EO. Interestingly, 40% of patients did not spontaneously mention the use of EOs, and only 33% received advice on their use at the time of purchase.
Patch tests with the BSE, limonene and linalool HP, and oxidized tea tree oil is sufficient to detect most EO-sensitized patients. The most important is to test the patient's own used EOs.
分析对自身精油(EO)过敏患者的基础系列(BSE)和精油贴斑测试系列(EOS)的临床特征和敏感性。
我们分析了患者档案中包含的问卷中获得的临床数据和 BSE 与 EOS 的斑贴试验结果,以及 EO 的使用方式。
研究纳入了 42 名(79%为女性,平均年龄 50 岁)过敏性接触性皮炎(ACD)患者,8 名患者需要住院治疗。所有患者均对自身使用的 EO 过敏,主要为薰衣草(Lavandula augustifolia,8000-28-0)、茶树(Melaleuca alternifolia leaf oil,68647-73-4)、瑞香(Cinnamomum camphora oil,92201-50-8),有 2 例归因于蜡菊(helichrysum italicum flower absolute,90045-56-0)。71%的患者对香料混合物 I 或 II 呈阳性斑贴试验,9%仅对 EOS 呈阳性,4%仅对其个人 EO 呈阳性。有趣的是,40%的患者并未主动提及使用 EO,只有 33%的患者在购买时收到了使用建议。
BSE、柠檬烯和芳樟醇 HP 以及氧化茶树油的斑贴试验足以检测出大多数 EO 过敏患者。最重要的是要测试患者自身使用的 EO。