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化妆品香料安全性的监管框架:全球概述。

Regulatory frameworks for fragrance safety in cosmetics: a global overview.

作者信息

Rana Priyanka, Pathania Diksha, Gaur Prakriti, Patel Sunil Kumar, Bajpai Medha, Singh Neera Tewari, Pandey Ruchi, Shukla Shakti Vinay, Pant Aditya Bhushan, Ray Ratan Singh, Dwivedi Ashish

机构信息

Photobiology Laboratory, Drug and Chemical Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Qaisar Bagh, Lucknow, 226001 Uttar Pradesh India.

Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002 India.

出版信息

Toxicol Res. 2025 Mar 1;41(3):199-220. doi: 10.1007/s43188-025-00283-2. eCollection 2025 May.

Abstract

Fragrances play a crucial role in cosmetic products, influencing consumer preferences and enriching sensory experiences. However, making sure these products are safe, especially concerning natural and synthetic fragrances, requires robust regulatory frameworks. This review offers a global perspective on the regulatory systems governing the safety of fragrances. It begins by examining the fundamental differences between natural and synthetic fragrances, highlighting their origins and unique safety considerations. Natural fragrances, sourced from botanicals like essential oils, have a long history of human exposure. Synthetic fragrances, on the other hand, are artificially manufactured compounds that often lack sufficient safety data, thereby requiring strict regulation. Various countries have developed safety guidelines to address concerns such as skin sensitization, allergies, and health risks associated with fragrance use. This article provides a comprehensive analysis of these global regulatory frameworks, emphasizing both commonalities and disparities in safety standards for natural and synthetic fragrances. It also discusses ongoing efforts to harmonize regulations and improve fragrance safety in cosmetics. By offering this in-depth overview of regulatory approaches, the article serves as a valuable resource for cosmetics industry professionals. It provides insights into the evolving landscape of cosmetics regulations worldwide, aiding stakeholders in navigating the complexities of natural and synthetic fragrance safety and ultimately safeguarding consumer well-being.

摘要

香料在化妆品中起着至关重要的作用,影响着消费者的偏好并丰富感官体验。然而,确保这些产品的安全性,尤其是天然香料和合成香料的安全性,需要健全的监管框架。本综述提供了关于香料安全性监管体系的全球视角。首先,它审视了天然香料和合成香料之间的根本差异,强调了它们的来源和独特的安全考量。源自精油等植物性原料的天然香料,人类接触它们已有很长历史。另一方面,合成香料是人工制造的化合物,往往缺乏足够的安全数据,因此需要严格监管。各国已制定安全指南,以应对诸如皮肤致敏、过敏以及与香料使用相关的健康风险等问题。本文对这些全球监管框架进行了全面分析,强调了天然香料和合成香料安全标准的共性与差异。还讨论了为协调法规和提高化妆品香料安全性而正在做出的努力。通过对监管方法进行深入概述,本文为化妆品行业专业人士提供了宝贵资源。它深入洞察了全球化妆品法规的不断演变,帮助利益相关者应对天然香料和合成香料安全的复杂性,并最终保障消费者的健康。

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Regulatory frameworks for fragrance safety in cosmetics: a global overview.化妆品香料安全性的监管框架:全球概述。
Toxicol Res. 2025 Mar 1;41(3):199-220. doi: 10.1007/s43188-025-00283-2. eCollection 2025 May.

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